Triamcinolone With Vitamin D Synergistic Efficacy in Psoriasis
Who is this study for? Patients with mild to moderate psoriasis
What treatments are being studied? Triamcinolone cream+Vitamin D3
Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement, Drug
Study Type: Interventional
Study Phase: Early Phase 1
SUMMARY
These studies are designed to assess the synergistic efficacy of topical 0.1% triamcinolone cream paired with 40,000 IU of oral vitamin D3 daily in treating mild to moderate psoriasis. The study is designed to have all subjects treated with triamcinolone cream (TAC) for 4 weeks, then will be randomized 1:1 into vitamin D3 or placebo for an additional 12 weeks. At that time, the study will become open-label and all subjects will be placed on (or continue) vitamin D3 for an additional 12 weeks. The study will take place over 28 weeks total.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age 18 and older
• Mild to severe plaque psoriasis (2% or greater Body Surface Area; Psoriasis Area and Severity Score of 2 or greater; Investigator Grade Assessment of mild-severe)
Locations
United States
Ohio
Wright State Physicians
RECRUITING
Fairborn
Contact Information
Primary
Manager, Clinical Research Operations
pturesearch@wrightstatephysicians.org
937-245-7500
Backup
Regulatory Specialist
pturesearch@wrightstatephysicians.org
937-245-7500
Time Frame
Start Date: 2019-10-16
Estimated Completion Date: 2026-12
Participants
Target number of participants: 24
Treatments
Experimental: Triamcinolone Cream + Vitamin D3
This arm will continue to take Vitamin D3 at Week 16 to Week 28.
Placebo_comparator: Triamcinolone Cream + Placebo
Starting at Week 16, this arm will be given Vitamin D3 to take until Week 28.
Related Therapeutic Areas
Sponsors
Leads: Wright State University