Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Early Phase 1
SUMMARY
Deep brain stimulation (DBS) is used to treat epilepsy in cases where patients are medically refractory and are not candidates for surgical resection. This therapy has been shown to be effective in seizure reduction, yet very few patients achieve the ultimate goal of seizure freedom. Implantable neural stimulators (INSs) have many parameters that may be adjusted, and could be tuned to achieve very patient specific therapies. This study will develop a platform for stimulation setting optimization based on power spectral density (PSD) measures.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• medically refractory epilepsy
• already have a deep brain stimulator in place
Locations
United States
Minnesota
University of Minnesota
RECRUITING
Minneapolis
Contact Information
Primary
Alec Jonason
jonas074@umn.edu
612-624-3127
Time Frame
Start Date: 2023-09-15
Estimated Completion Date: 2030-01-15
Participants
Target number of participants: 20
Treatments
Experimental: Stimulation Group A
Participants with already implanted DBS will receive stimulation order 1. PS, OS, OS.
Experimental: Stimulation Group B
Participants with already implanted DBS will receive stimulation order 1. OS, PS, OS.
Experimental: Stimulation Group C
Participants with already implanted DBS will receive stimulation order 1. OS, OS, PS.
Related Therapeutic Areas
Sponsors
Leads: University of Minnesota