Neutrophil Phenotypic Profiling and Organ Injury Assessment in Patients With Sepsis

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

In this research study we want to learn more about the character of neutrophils that are present in the blood of children with sepsis. Sepsis is a severe type of infection, affecting various parts of the body. Neutrophils are a type of white blood cell that are part of the body's immune system. Even though neutrophils are important in getting rid of germs, they also may be harmful to parts of the body by causing injury in organs in patients with sepsis. Neutrophils can change their character in sepsis. Because of this, it is important for doctors to know what kind of neutrophils are in the blood of children with sepsis so that they can work to develop therapies to prevent these cells from being harmful.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 1 month
Maximum Age: 17
View:

• Are \< 18 years old

• Meet the definition of sepsis described in the study design section above. Patients will be eligible for enrollment as control patients if they

• Are \< 18 years old

• Are scheduled for an elective surgical procedure and need preoperative blood draw or will have an intravenous catheter placed for the purpose of their surgical procedure.

Locations
United States
Massachusetts
Boston Children's Hospital
RECRUITING
Boston
Contact Information
Primary
Koichi Yuki, MD
koichi.yuki@childrens.harvard.edu
617-355-6225
Time Frame
Start Date: 2020-08-04
Estimated Completion Date: 2025-12-01
Participants
Target number of participants: 72
Treatments
Sepsis
Control
Related Therapeutic Areas
Sponsors
Leads: Boston Children's Hospital

This content was sourced from clinicaltrials.gov