Population Pharmacokinetic of Piperacillin/Tazobactam in Maternal and Neonatal Populations With High Risk for EOS
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Observational
SUMMARY
The purpose of this study is to describe the population pharmacokinetic characteristics of piperacillin/tazobactam after intravenous administration in pregnant women during pregnancy and delivery, and to evaluate pharmacodynamic effectiveness and safety of piperacillin/tazobactam in pregnant women whose baby are at high risk of developing early-onset sepsis after birth.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Healthy Volunteers: f
View:
• Patients over 18 years old;
• Pregnant women whose baby are at high risk of developing early-onset sepsis after birth have indications to use preventive or therapeutic antibiotics, and the antibiotics used are PIP/TAZO；
• Patients and their families are fully aware of the research content and sign the informed consent form.
Locations
Other Locations
China
Shandong Provincial Hospital
RECRUITING
Jinan
Contact Information
Primary
Wei Zhao, Ph.D
zhao4wei2@hotmail.com
86053188383308
Time Frame
Start Date: 2023-09-30
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 50
Related Therapeutic Areas
Sponsors
Leads: Shandong University
Collaborators: Shandong Provincial Hospital