Early Identification of Sepsis-associated Acute Kidney Injury Using Ultrasonography Measurements and Renin and Angiotensin Levels in Children and Adults.
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
Prospective observational cohort study; pediatric sepsis vs. healthy pediatric subjects and pediatric sepsis with acute kidney injury (AKI) vs without AKI. Blood samples and renal ultrasound will be collected on sequential days for septic subject and one time for the healthy patients. Enzyme-linked immunosorbent assays (ELISA) with be run on serum plasma to compare the renin-angiotensin-aldosterone system (RAAS) between groups.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 1 day
Maximum Age: 18
Healthy Volunteers: t
View:
• pediatric patients age 1 days - 18 years old with sepsis or age 1 day - 18 years and healthy.
Locations
United States
New York
Cohen Children's Medical Center
RECRUITING
New Hyde Park
Contact Information
Primary
Grace Fisler, MD
gfisler@northwell.edu
203-671-0654
Time Frame
Start Date: 2024-01-24
Estimated Completion Date: 2025-06-01
Participants
Target number of participants: 74
Treatments
Pediatric Septic
1 day -18 year olds admitted to the ICU meeting criteria for sepsis define as pSOFA \>/= 2 and/or Phoenix score.
Healthy
1 day - 18 year old; healthy outpatient
Related Therapeutic Areas
Sponsors
Leads: Northwell Health