ANGIOtensin II for Septic Shock in the Emergency Department: ANGIO-ED Study
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
This pilot study will enroll 20 patients with septic shock and require emergent vasopressor support in the emergency department (ED). The primary objective of the study is to determine the feasibility of early peripheral administration of angiotensin II for treatment of septic shock in the ED
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 99
Healthy Volunteers: f
View:
• Age ≥18; and
• Requiring norepinephrine at a dose of 0.05-0.25 mcg/kg/min mcg/kg/minute despite adequate fluid resuscitation; and
• Receiving intravenous antibiotics or clinician's intention to administer antibiotics at the time of enrollment; and
• Can provide written informed consent (or legally authorized representative).
Locations
United States
Iowa
University of Iowa Hospitals and Clinics
RECRUITING
Iowa City
Contact Information
Primary
Brett Faine, PharmD
brett-faine@uiowa.edu
+1 319 356 2577
Time Frame
Start Date: 2025-04-01
Estimated Completion Date: 2026-06-30
Participants
Target number of participants: 20
Treatments
Experimental: Angiotensin II Infusion
Related Therapeutic Areas
Sponsors
Leads: Brett A Faine