Clinical Study of the Effect of Intravenous Hydrocortisone Combined With Vitamin C and Vitamin B1 Infusion on Prognosis and Sublingual Microcirculation in Elderly Patients With Sepsis or Septic Shock.
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study intends to observe the effect of intravenous hydrocortisone combined with vitamin C and vitamin B1 infusion on the prognosis and sublingual microcirculation in patients with sepsis or septic shock through a prospective randomized controlled study method.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 60
Maximum Age: 85
Healthy Volunteers: f
View:
• Age ≥60 and ≤85 years old;
• Diagnosis of sepsis or septic shock;
• Clinical judgment for hydrocortisone treatment;
• Signing Informed Consent.
Locations
Other Locations
China
Zhongda Hospital Southeast University
RECRUITING
Nanjing
Contact Information
Primary
Jingyuan Xu, M.D.
xujingyuanmail@163.com
8602583262550
Time Frame
Start Date: 2024-07-01
Estimated Completion Date: 2025-11-30
Participants
Target number of participants: 40
Treatments
Experimental: metabolic resuscitation agents
Patients in the intervention group received IV hydrocortisone (200mg every 24 hours), vitamin C (1.5g every 6 hours), and thiamine (200 mg every 12 hours).
Placebo_comparator: hydrocortisone
Patients in the control group received IV hydrocortisone (200mg every 24 hours).
Related Therapeutic Areas
Sponsors
Leads: Southeast University, China