The Effect of Critical Ultrasonography Guided Precise Fluid Management in Patients With Sepsis or Septic Shock: A Single-center Randomized Controlled Trial
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study aims to assess whether procedural critical ultrasonography guided precise fluid management (CUGP) can affect the clinical fluid management strategy and improve the outcomes of patients with sepsis or septic shock.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• 1\. Age ≥ 18 years old;
• 2\. Estimated length of ICU stay ≥ 24 hours;
• 3\. Diagnosis according to the Sepsis 3.0 criteria, which included:
• a. suspected or confirmed infections supported by clinical evidence and/or positive microbiological findings;
• b. the sepsis related organ failure assessment (SOFA) score ≥ 2.
Locations
Other Locations
China
Department of Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITING
Wuhan
Contact Information
Primary
Shusheng Li, PhD
lishusheng@hust.edu.cn
86-13971086498
Backup
Yi Bian, Doctor
bianyi2526@163.com
86-15102710366
Time Frame
Start Date: 2025-04-01
Estimated Completion Date: 2026-05-31
Participants
Target number of participants: 118
Treatments
Experimental: CUGP group
In the CUGP group, ultrasonographic assessment was performed by a team of trained critical ultrasonography physicians at enrollment, 1 hour, 3 hours, 6 hours, 12 hours, 24 hours, 48 hours, and 72 hours thereafter, respectively.
No_intervention: usual care group
The usual care group used conventional hemodynamic monitoring methods for monitoring and decision-making about fluid management. Records were made at enrollment, 1 hour, 3 hours, 6 hours, 12 hours, 24 hours, 48 hours, and 72 hours thereafter, respectively.
Related Therapeutic Areas
Sponsors
Leads: Shusheng Li