'5 Rs to Rescue' A Cluster Trial With an Embedded Process Evaluation

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

'Failure to rescue' describes the preventable death of a patient following the absence of timely identification and treatment of a complication after surgery. The absence of systems contributes to the higher mortality post-surgery in Africa compared to high-income countries. To mitigate this, a complex quality improvement (QI) intervention has been designed focusing on improving five main areas of patient management following surgery termed as '5 Rs to Rescue'. The study will take place in 20 centers in 4 countries - Ethiopia, South Africa, Tanzania, and Uganda. This a multi-center, mixed methods, cluster trial with a baseline assessment to evaluate the efficacy of the QI intervention. To study is aimed to evaluate whether implementation of the '5 Rs to Rescue' quality improvement intervention increases surveillance for patients at risk of 'failure to rescue' after surgery in hospitals in Africa. The '5 Rs to Rescue' includes: 1. Risk assessment using the ASOS risk score for all surgical patients, 2. Recognition of patient deterioration by regular, protocolized vital signs monitoring plus use of an Early Warning Score (EWS) system. 3. Response to deterioration by protocolized escalation based upon EWS plus protocolized care pathways for common complications (hypoxia, hypovolemia, sepsis). 4. Reassessment following deterioration by protocolized re-assessment based upon EWS, and 5. Reflection on care provided following a patient's deterioration or death using a structured review tool at regular reflection meetings.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 100
Healthy Volunteers: f
View:

• Patients aged 18 years and older undergoing any surgery, who receive postoperative care on a participating ward

Locations
Other Locations
South Africa
Groote Schuur Hospital
RECRUITING
Cape Town
Contact Information
Primary
Margot Flint, PhD
margot.flint@uct.ac.za
+27721222111
Backup
Bruce Biccard, MBChB; PhD
bruce.biccard@uct.ac.za
+27761606387
Time Frame
Start Date: 2024-09-01
Estimated Completion Date: 2026-09-01
Participants
Target number of participants: 6000
Treatments
High-risk surgical patients
High-risk patients (ASOS Surgical Risk Calculator Score \>10) having surgery, defined as ≥7 high risk patients having surgery per week.
Related Therapeutic Areas
Sponsors
Leads: University of Cape Town

This content was sourced from clinicaltrials.gov