Locomotor Recovery and Compensation Post-stroke (LRC)

Who is this study for? Patients with Stroke
What treatments are being studied? High-Intensity Training Focused on Stepping in Variable Contexts
Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The proposed research will characterize of the time course of neurological and locomotor recovery as well as development of compensatory strategies throughout sub-acute and chronic phases post stroke. In addition, we will also investigate the extent to which measures of recovery and compensation are malleable and can be altered with specific interventions in both the early and late stages post-stroke. Delineation of the time course of development and magnitude of patterns of recovery and compensation should result in alternative predictive rules' regarding how patients early post-stroke could recovery functional and neurological function.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:

• individuals early post-stroke (\<15-30 days)

• first ever stroke

• unilateral hemiparesis

• currently receiving inpatient rehabilitation

• ability to follow 1-step commands

• provision of informed consent

• medical clearance from the rehabilitation physician to participate. \

Locations
United States
Indiana
Rehabilitation Hospital of Indiana
RECRUITING
Indianapolis
Contact Information
Primary
Thomas G Hornby
tghornby@Iu.edu
3173292353
Backup
Chris Henderson
henderce@iu.edu
3173292353
Time Frame
Start Date: 2021-09-01
Estimated Completion Date: 2028-02-28
Participants
Target number of participants: 150
Treatments
Other: Phase 1
Observational evaluations for 6 months followed by 3-4 months of high-intensity training (HIT)
Other: Phase 2
Observational evaluations for 1 month followed by 3-4 months of high-intensity training (HIT)
Related Therapeutic Areas
Sponsors
Collaborators: Rehabilitation Hospital of Indiana, National Institute of Neurological Disorders and Stroke (NINDS)
Leads: Indiana University

This content was sourced from clinicaltrials.gov