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Precise Antiplatelet THerapy Guided by Platelet Aggregation Function in Ischemic STROKE

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

1. Main objective: To explore the efficacy of precise antiplatelet therapy guided by platelet aggregation function in reducing the incidence of 30 day platelet hyperresponsiveness in patients with non-cardiogenic ischemic stroke. 2. Secondary objective: To explore the efficacy and safety of antiplatelet therapy in patients with non-cardiogenic ischemic stroke under the guidance of platelet aggregation function.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Aged from 18 to 80 years;

• Diagnosed with non-cardiogenic ischemic stroke according to WHO criteria, confirmed by cranial CT or MRI to exclude hemorrhagic stroke.;

• First stroke onset ≥ 1 month and ≤ 3 months;

• mRS Score \<=2 points;

• Undergoing antiplatelet therapy with 100mg aspirin daily for at least 8 days;

• Informed consent signed by the patient or their family member.

Locations
Other Locations
China
Sichuan Provincial People's Hospital
RECRUITING
Chengdu
Contact Information
Primary
Jie Yang, doctor
yangjie1126@163.com
+86 13678130516
Backup
YaPeng Lin, doctor
linyapengsjnk@163.com
+86 13540389801
Time Frame
Start Date: 2023-01-01
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 1020
Treatments
Experimental: Precision Antiplatelet Therapy Trial Group
Platelet function testing guides antiplatelet drug selection
Active_comparator: Traditional Antiplatelet Therapy Control Group
Aspirin 100mg orally once a day
Related Therapeutic Areas
Sponsors
Leads: Sichuan Provincial People's Hospital

This content was sourced from clinicaltrials.gov