Exploring Vascular Contributions to Cognitive Decline and Dementia
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
The ENIGMA study is a single-centre prospective clinical observational study with the aim to investigate vascular contributions to cognitive decline and dementia. By studying MRI-defined capillary dysfunction and EV profiles, the ENIGMA study links novel imaging and basic research techniques to a clinical cohort of stroke patients. With this study we hope to enhance the understanding of the mechanisms behind post-stroke cognitive decline and dementia.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 60
Healthy Volunteers: f
View:
• AIS or TIA with a clinically relevant diffusion restriction identified on MRI DWI-sequence on admission
• Admittance within 24 hours from symptom onset
• Age ≥ 60
Locations
Other Locations
Denmark
Aarhus University Hospital
RECRUITING
Aarhus
Contact Information
Primary
Janne Kaergaard Mortensen, PhD
janne.k.mortensen@clin.au.dk
+4521156903
Backup
Sigrid Vestergaard, MD
sigrso@rm.dk
+4521456903
Time Frame
Start Date: 2021-04-01
Estimated Completion Date: 2025-06-01
Participants
Target number of participants: 140
Related Therapeutic Areas
Sponsors
Collaborators: University of Aarhus
Leads: Aarhus University Hospital