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Clinical Characteristics and Prognosis of Acute Stroke in Pregnancy and Puerperium: A Retrospective, Observational, Nationwide, Multicenter Study

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The objectives of this study are: (1) to describe the detailed clinical characteristics and prognosis of ASPP patients in order to explore the risk factors of ASPP, and to compare the short-term and long-term functional recovery outcomes between them and their controls; (2) to evaluate the risk of recurrent stroke, particularly during subsequent pregnancies, in ASPP patients; (3) to assess the short-term and long-term outcomes of their offsprings and their future development status. This study is divided into three parts. The first part is a case-control study to explore the risk factors of ASPP and the predictors of the prognosis of ASPP patients. The second part is a cohort study to evaluate the impact of ASPP on the risk of recurrent stroke. The third part is a cohort study to assess the impact of ASPP on the short-term and long-term outcomes of their offsprings by comparing the offsprings of ASPP patients with the offsprings of non-ASPP participants.

Eligibility
Participation Requirements
Sex: Female
Healthy Volunteers: f
View:

• Female patients ≥18 years of age;

• Patients or their legally acceptable representatives or relatives agree to collect personal information for this study and sign an oral or online written informed consent.

• Female patients ≥18 years of age;

• Patients in pregnancy or within 6 weeks postpartum;

• Patients or their legally acceptable representatives or relatives agree to collect personal information for this study and sign an oral or online written informed consent.

Locations
Other Locations
China
Beijing Tiantan hospital
RECRUITING
Beijing
Contact Information
Primary
Zihan Yin, MD
neuroyinzihan@foxmail.com
+8613718234402
Backup
Zhongji Zhang, MD
zzj0202@outlook.com
+8613901318591
Time Frame
Start Date: 2024-07-31
Estimated Completion Date: 2025-06
Participants
Target number of participants: 1200
Treatments
ASPP
Patients with acute stroke in pregnancy or puerperium
Pregnant/Puerperal Non-Stroke
Pregnant or puerperal participants without any history of stroke
Non-Pregnant Stroke
Non-pregnant or non-puerperal participants with a recent acute stroke event
Related Therapeutic Areas
Sponsors
Collaborators: The Second Affiliated Hospital of Hainan Medical University, RenJi Hospital, Tibetan Second People's Hospital, West China Hospital, Qianfoshan Hospital, Xiangya Hospital of Central South University, Binzhou Medical University, Shenzhen Second People's Hospital, First Affiliated Hospital of Harbin Medical University, Xinxiang Central Hospital, Second Affiliated Hospital of Soochow University, Affiliated Hospital of Nantong University, The First Affiliated Hospital of Nanchang University, The First Affiliated Hospital of University of Science and Technology of China, First Affiliated Hospital Xi'an Jiaotong University, Lanzhou University Second Hospital, The Affiliated Hospital of Qingdao University, Affiliated Hospital of Jiangnan University, Tianjin Huanhu Hospital, Baotou Central Hospital, Jiangyin People's Hospital, The First Affiliated Hospital of Zhengzhou University, Chongqing Medical University, Second Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Tianjin Medical University General Hospital, Zhejiang Provincial People's Hospital
Leads: Beijing Tiantan Hospital

This content was sourced from clinicaltrials.gov