Effect of Inspiratory Muscle Training on Respiratory Function, Diaphragm Thickness, Balance Control, Exercise Capacity and Quality of Life in People After Stroke: a Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study is designed to explore the effects of a 4-week protocol of inspiratory muscle training (IMT) at 50% maximum inspiratory pressure (MIP) on respiratory function, diaphragm thickness, balance control, exercise capacity, and quality of life in people after stroke. To ascertain the effect of IMT on the relationship between diaphragm muscle contraction and activation of other trunk muscles, this study also explores whether any effect of the 4-week IMT protocol on balance control is associated with changes in the anticipatory posture adjustments (APAs) time - the onset time of postural muscles during a required task (e.g., the rapid shoulder flexion test).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Maximum Age: 80
Healthy Volunteers: f
View:

• Age ≥ 40 years and \< 80 years;

• breathing spontaneously;

• clinically diagnosed with ischemic and/or haemorrhagic stroke;

• duration of stroke from onset falls within 1 month to 12 months after diagnosis;

• no thoracic or abdominal surgery within the last 6 months;

• able to understand and follow verbal instructions;

• no facial palsy, or mild facial palsy without limitation of labial occlusion;

• able to maintain a resting sitting posture without feet support for at least 30 seconds;

• no cognitive impairment (Montreal Cognitive Assessment (MoCA) score ≥ 26);

• able to independently walk at least 10 meters with or without an assistive device.

Locations
Other Locations
China
Shenzhen Second People's Hospital
RECRUITING
Shenzhen
Contact Information
Primary
Fang LIU
s1350035@live.hkmu.edu.hk
+86 13603049475
Backup
William Wai-nam Tsang
wntsang@hkmu.edu.hk
085239708703
Time Frame
Start Date: 2025-02-21
Estimated Completion Date: 2026-06-15
Participants
Target number of participants: 84
Treatments
Sham_comparator: Group A (sham IMT- stable group)
conventional treatment + sham IMT
Experimental: Group B (IMT-stable group)
conventional treatment + target IMT while sitting on a stable surface
Experimental: Group C (IMT-unstable group)
conventional treatment + target IMT while sitting on an unstable surface
Related Therapeutic Areas
Sponsors
Leads: Hong Kong Metropolitan University

This content was sourced from clinicaltrials.gov