ReadMap: Reading in Stroke Alexia and Typical Aging

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Loss of reading ability due to stroke, called alexia, likely affects over a million Americans at any given time and causes difficulty performing many daily life functions, such as paying bills, using email/text, reading for pleasure, and reading signs in the community. Understanding the brain and cognitive basis of alexia could improve diagnosis and treatment of this important problem. In this study, the investigators will perform a large-scale behavioral and brain imaging study of stroke survivors and typical older adults to improve our understanding of the brain and cognitive basis of reading in both of these groups. Participants will complete a battery of tests of reading, speech, language, and thinking abilities. In addition, some participants will complete an MRI. Sessions will be completed across approximately 2-6 weeks, but may be extended depending on participants' schedules and availability. Some participants will be invited to repeat these procedures once or twice in approximately 3-12 months to monitor for changes in reading abilities and MRI measurements over time.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

⁃ Stroke Survivors:

• Age \>= 18

• Learned English at 8 years or younger

• Brain injury resulting from stroke

⁃ Controls:

• Age \>= 18

• Learned English at 8 years or younger

Locations
United States
Washington, D.c.
Georgetown University Medical Center
RECRUITING
Washington D.c.
Contact Information
Primary
Alycia Laks, MS, CCC-SLP
crlab@georgetown.edu
202-687-5205
Time Frame
Start Date: 2023-01-12
Estimated Completion Date: 2028-08-31
Participants
Target number of participants: 300
Treatments
Stroke Survivors
Participants have had a left-hemisphere stroke, or a stroke elsewhere in the brain causing aphasia or alexia (i.e., reading difficulties). They are given a series of standardized and in-house tests of reading, language and cognition to provide a detailed profile of strengths and weaknesses, plus an MRI.
Controls
Participants are matched to the stroke cohort in age, educational background, race, and gender but have no history of brain injury. They are also given a series of standardized and in-house tests of reading, language and cognition to provide a detailed profile of strengths and weaknesses, plus an MRI.
Related Therapeutic Areas
Sponsors
Collaborators: National Institute on Deafness and Other Communication Disorders (NIDCD), MedStar National Rehabilitation Network
Leads: Georgetown University

This content was sourced from clinicaltrials.gov