Graviceptive Neglect After Stroke: Clinical, Neuroanatomical and Physiological Effects of Focal Neuromodulation
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Phase 1/Phase 2
SUMMARY
We aim to determine if targeted high-definition transcranial direct current stimulation (HD-tDCS) can safely correct errors in visual verticality perception in patients after stroke affecting either hemisphere.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• Supratentorial ischemic stroke diagnosed by neuroimaging and clinical analysis;
• Clinically stable (stable vital signs for 24 hours; no chest pain in the last 24 hours; no significant arrhythmia; no evidence of deep vein thrombosis);
• Normal or corrected-to-normal vision;
• No previous experience with HD-tDCS;
• Ability to provide informed consent (patient or legal representative);
• Ability to comply with the intervention and assessment schedule of the protocol.
• Presence of visual verticality misperception.
Locations
Other Locations
Brazil
Ribeirão Preto Medical School, University of São Paulo
RECRUITING
Ribeirão Preto
University of São Paulo, Ribeirão Preto Medical School
NOT_YET_RECRUITING
Ribeirão Preto
Contact Information
Primary
Taiza G. S. Edwards, PhD
taiza@fmrp.usp.br
+55-16-33153379
Backup
Lizanilda Albuquerque, BSc
lizanilda@usp.br
+55-16-36021202
Time Frame
Start Date: 2025-01-03
Estimated Completion Date: 2026-01-15
Participants
Target number of participants: 28
Treatments
Experimental: Active HD-tDCS
Participants will receive six sessions of 2mA active HD-tDCS cathode center over the contralesional TPJ for 20 minutes, 3 times daily for 2 days with session intervals greater than 3 hours.
Sham_comparator: Sham HD-tDCS
Participants will receive six sessions of 2mA sham HD-tDCS cathode center over the contralesional TPJ for 20 minutes, 3 times daily for 2 days with session intervals greater than 3 hours.
Related Therapeutic Areas
Sponsors
Collaborators: Fundação de Amparo à Pesquisa do Estado de São Paulo, Viasonix, FBX Medical, Thomas Jefferson University, Phelcom
Leads: University of Sao Paulo