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Initial Predictors of Long-term Brain Resilience After Minor Ischemic Stroke: a Study Nested in the Brest Stroke Population-based Registry

Status: Recruiting
Location: See location...
Intervention Type: Other, Diagnostic test, Genetic
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The objective of this clinical trial is to develop, based on patients' initial characteristics (in the first few weeks following the stroke), a predictive model of quality of life more than 4 years after the stroke in patients who have suffered a minor ischemic stroke. The main question it aims to answer is: \- Is it possible to predict the quality of life of patients who have suffered a minor ischemic stroke based on their initial characteristics? To do this, retrospective and prospective data collected as part of the study will be analyzed using a conventional statistical approach and algorithms based on AI approaches in order to create a predictive model. Participants will be asked to: * Complete questionnaires * Provide a saliva sample (optional) * Undergo an MRI scan (optional)

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Cases of stroke in the Brest Stroke Registry (BSR)

• Ability to sign informed consent

• Patients followed-up \> 4 years during the study period

• NIHSS score ≤ 5 on admission

• First stroke above 18 and before 75-year old

• Rankin before stroke \< 1

• Possibility to draw saliva samples for genomic study

• Possibility to perform Cerebral MRI

Locations
Other Locations
France
CHU de Brest
RECRUITING
Brest
Contact Information
Primary
Serge TIMSIT, Pr
serge.timsit@chu-brest.fr
298147349
Time Frame
Start Date: 2025-06-18
Estimated Completion Date: 2028-12-18
Participants
Target number of participants: 1000
Treatments
Other: Minor ischemic stroke
Patients registered in the Brest Stroke Registry who have been a minor stroke more than 4 years ago
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Brest

This content was sourced from clinicaltrials.gov