Comparison of 5G Mobile Stroke Unit to Standard Management by Emergency Medical Services For Acute Ischemic Stroke Treatment：A Multicenter, Prospective, Open-label, Blinded Endpoint , Week-wise Randomized, Controlled Trial
While Mobile Stroke Units (MSUs) are considered as a relatively new model for acute stroke treatment, 5G Mobile Stroke Units (5G MSUs) have already come into service for stroke treatment in some parts of China. Since limited evidence has been found to suggest their advantages over conventional Emergency Medical Services (EMS), well-conducted clinical studies are required to further assess their effectiveness and safety. This study aims to evaluate whether 5G MSUs outperform standard management (SM) by EMS in terms of functional outcomes of acute ischemic stroke (AIS) patients within 4.5 hours after symptom onset in urban and rural areas of China.
• History and physical/neurological examination consistent with acute stroke.
• Age≥18.
• Last seen normal within 4hr 30 min of symptom onset.
• Pre-stroke modified Rankin scale ≤3（Being able to ambulate）.
• No rt-PA/TNK exclusions per guidelines, prior to CT scan or baseline labs.
• Informed consent obtained from patient (if competent) or legal representative.