Synergistic Potential of Non-invasive Brain and Spinal Cord Stimulation for Improving Sensorimotor and Cognitive Functions After Neurological Injury
The goal of this clinical study is to investigate the potential synergy between non-invasive brain and spinal cord stimulation administered during a cognitive-motor task, in terms of their immediate effects on sensorimotor and cognitive functions after neurological injuries affecting the upper limb (cervical spinal cord injury and stroke). Secondary objectives are to evaluate the relevance of anatomical MRI, functional MRI, and neurophysiological measurements for optimizing and predicting the effects of these different interventions.
⁃ CONTROL GROUP:
• Over 18 years of age
• Participant who has signed an informed consent form
• Participant who is affiliated with and covered by the social security system
⁃ POST-STROKE GROUP:
• Over 18 years of age
• Who sustained a stroke more than 3 weeks ago
• Considered medically stable by the medical investigator
• Who has signed an informed consent form
• Affiliated with and covered by the social security system
⁃ SCI GROUP:
• Over 18 years of age
• Considered to have a complete or incomplete spinal cord injury (i.e., with a score on the Spinal Injury Association (ASIA) Impairment Scale (AIS) score from A to D)
• Considered medically stable by the investigating physician
• Presenting with quadriplegia due to cervical injury
• Who has signed an informed consent form
• Affiliated with and covered by the social security system.