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Protecting the Brain From Post-Stroke Cognitive Impairment and Dementia With Multimodal Exercise Training

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The rates of cognitive decline and dementia after stroke are disproportionately high. Strategies that can protect the brain early after the stroke event could reduce the future risk of cognitive decline and dementia in these patients. Although physical exercise is usually recommended after stroke, there is very little information about the protective effect of exercise implemented in early stages of recovery as a potential protective measure against cognitive decline and dementia risk in these patients. This study will investigate the effect of a multimodal exercise intervention implemented early after the stroke event on cognition and on a selected group of markers that can predict cognitive decline and dementia risk.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Maximum Age: 85
Healthy Volunteers: f
View:

• have had a first-ever ischemic/hemorrhagic stroke confirmed by MRI/CT 0-6 months prior to participation.

• Able to independently walk at least 10 meters (assistive devices permitted) and capable of following instructions will be required.

Locations
Other Locations
Canada
McMaster University
ACTIVE_NOT_RECRUITING
Hamilton
Jewish Rehabilitation Hospital
RECRUITING
Laval
Contact Information
Primary
Marc Roig
marc.roigpull@mcgill.ca
514-398-4400
Time Frame
Start Date: 2026-01-01
Estimated Completion Date: 2030-12-31
Participants
Target number of participants: 126
Treatments
Experimental: Multimodal Exercise
Twelve weeks of combined resistance and cardiovascular training held three times per week.
Active_comparator: Balance, Toning and Stretching
Twelve weeks of combined balance, toning, and stretching training held three times per week.
Related Therapeutic Areas
Sponsors
Collaborators: Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal, Jewish Rehabilitation Hospital, Montreal Neurological Institute and Hospital, McMaster University
Leads: McGill University

This content was sourced from clinicaltrials.gov