Evaluation of Spinal Cord Ischemia and Mortality and Morbidity After Endovascular Repair of Pararenal and Thoracoabdominal Aortic Aneurysm Using Surgeon-Modified Endografts

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The primary objective is to evaluate the safety and effectiveness of surgeon modified endografts for the treatment of pararenal and thoracoabdominal aortic pathology in patients who are not candidate for traditional open repair due to comorbid issues and their anatomy is not amenable to commercially available endografts.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Provision of signed and dated informed consent form

• Male or female, aged ≥18 years

• Expected survival beyond 1 year following successful aneurysm repair

• Anatomy that would require coverage of the celiac artery, superior mesenteric artery (SMA), and/or renal arteries if conventional, FDA-approved endograft were implanted to obtain adequate sealing zone length

• Aneurysm of the thoracoabdominal or pararenal aorta with or without chronic dissection

• Adequate proximal zone of fixation

• Adequate distal zone of fixation

• No more than 5 non-aneurysmal visceral (celiac, SMA, or renal) arteries with diameters between 4-12mm

• Adequate arterial access for delivery system; use of iliac conduit is permitted as necessary

Locations
United States
Florida
Tampa General Hospital
RECRUITING
Tampa
University of South Florida - South Tampa Campus
RECRUITING
Tampa
Contact Information
Primary
Beth Montera
bmontera@usf.edu
8138447948
Backup
Konstantinos Arnaoutakis, MD
arnaoutakis@usf.edu
Time Frame
Start Date: 2023-06-06
Estimated Completion Date: 2029-08
Participants
Target number of participants: 30
Treatments
Experimental: Physician-modified endografts
For this clinical protocol, endografts which are commercially available will be modified in a sterile fashion on a back-table in the operating room.
Sponsors
Leads: Konstantinos Dean Arnaoutakis, MD

This content was sourced from clinicaltrials.gov