Comparación De La Eficacia Entre Biomarcadores Y Ecografía Con Contraste Frente a Angio-TC En El Seguimiento De Aneurismas De Aorta Abdominal (AAA) Tras Reparación Endovascular (EVAR)

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

This prospective observational study evaluates the efficacy of contrast-enhanced ultrasound and biomarker determination in the follow-up of patients with abdominal aortic aneurysm (AAA) treated with Endovascular Aneurysm Repair (EVAR). Currently, computed tomography angiography (CTA) is the standard for follow-up, although it has disadvantages such as radiation exposure and the use of iodinated contrasts. Contrast-enhanced ultrasound (CEUS), free of radiation and nephrotoxicity, and biomarkers could reduce the need for CTA minimizing the associated risks. Biomarkers will be measured before and after EVAR and CEUS will be performed at various time points and compared with CTA results to validate concordance and effectiveness in detecting endoleaks and aneurysm remodeling. The objectives include determining the efficacy of these combined methods and establishing a follow-up protocol that reduces exposure to radiation and iodinated contrast agents.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• patients with AAA under follow-up who are going to be treated with EVAR.

• signed informed consent to perform CTA, CEUS and for the determination of biomarkers.

Locations
Other Locations
Spain
Hospital La Fe
RECRUITING
Valencia
Contact Information
Primary
Juan Manuel Sanchís García
sanchis_juagar@gva.es
+34 961245655
Time Frame
Start Date: 2024-07-25
Estimated Completion Date: 2028-04-30
Participants
Target number of participants: 60
Treatments
Study cohort
Inclusion Criteria:~* patients with AAA under follow-up who are going to be treated with EVAR.~* signed informed consent to perform CTA, CEUS and for the determination of biomarkers.~Exclusion Criteria:~* patients with inflammatory abdominal aortic aneurysms or ruptured aneurysm.
Sponsors
Leads: Instituto de Investigacion Sanitaria La Fe

This content was sourced from clinicaltrials.gov