The Intervention Effect Of Alpha-Ketoglutarate On Abdominal Aortic Aneurysm Progression and Rupture: A Prospective, Randomized Parallel Controlled Study Based On Large Cohorts
The objective of this project is to define whether nutritional supplement (oral administration with alpha-ketoglutarate) capable of filling-up the citric acid cycle (anaplerotic therapy) can improve outcomes in patients with an abdominal aortic aneurysm of 39-49 mm in diameter on ultrasound imaging. Alpha-ketoglutarate is commonly used as a nutritional supplement specially by athletes to increase muscle strength. They can be mixed with formula or other foods. Subjects will be followed for up to 5 years.
• Presence of an infrarenal AAA with a maximum diameter of 39-49 mm;
• Han nationality;
• Between 50 years or more, no gender limit;
• No mental illness;
• No history of supplement allergy or supplement allergy;
• Subjects voluntarily participate in this study, sign an informed consent form, have good compliance, and cooperate with follow-up.