Abdominal obesity metabolic syndrome is a disease that is influenced by both genetic and environmental factors characterized by a clustering of insulin resistance, high levels of insulin, abnormal blood fats (lipids), high blood pressure, abdominal obesity, glucose intolerance or non-insulin dependent diabetes mellitus, and an increased risk of adverse cardiovascular events. There are different types of abdominal obesity metabolic syndrome, such as abdominal obesity metabolic syndrome 1 or 4. Factors that influence the development of abdominal obesity metabolic syndrome include age, smoking, alcohol, diet, and physical inactivity. Abdominal obesity metabolic syndrome occurs most often in Mexican American women.

Symptoms of abdominal obesity metabolic syndrome may include chest pain; radiating pain in chest, jaw, or down left arm (angina pectoris); swelling; abdominal obesity; high blood pressure; high blood triglycerides and low high-density lipoprotein levels; high fasting glucose levels; type 2 diabetes; coronary heart disease (plaque build-up in arteries; CHD); heart attack; and cardiac death.

Treatment for abdominal obesity metabolic syndrome focuses first on lifestyle changes, such as weight loss, exercise, healthy diet, and quitting smoking. Medications for treating abdominal obesity metabolic syndrome may include diabetes drugs; statins to lower blood lipids (fats), such as atorvastatin; blood pressure medications; and blood-thinning medications, such as aspirin or clopidogrel to prevent blood clots.