Effects of Dietary Nitrate in Women With Secondary Amenorrhea

Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Excessive exercise, disordered attitudes toward eating, physical and psychological stress, and/or hormonal imbalances may result in cessation of menstruation (secondary amenorrhea). The accompanying lack of estrogen may impair muscle power and oxygen recovery after exercise by reducing nitric oxide levels. The purpose of this study is to determine whether ingestion of beetroot juice containing nitrate, an alternative source of nitric oxide, can help reverse these changes.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 44
Healthy Volunteers: f
View:

• Women age 18-44 years old

• Missed \>3 consecutive periods in the last 12 months if previously regularly menstruating (average cycle 21-35 d) OR

• Missed \>6 consecutive periods in the last 12 month if previously irregularly menstruating (spontaneous menstruation, average cycle \<21 or \> 35 d)

Locations
United States
Indiana
Indiana University Indianapolis
RECRUITING
Indianapolis
Contact Information
Primary
Andrew R Coggan, PhD
mjfry@iu.edu
317-274-0656
Time Frame
Start Date: 2025-09-05
Estimated Completion Date: 2026-07
Participants
Target number of participants: 12
Treatments
Placebo_comparator: Placebo
Nitrate-free beetroot juice
Experimental: Nitrate
Nitrate-rich beetroot juice
Related Therapeutic Areas
Sponsors
Leads: Indiana University

This content was sourced from clinicaltrials.gov