Learn About Achard Syndrome

What is the definition of Achard Syndrome?
Achard syndrome, also known as Achard-Thiers syndrome, is a rare disorder characterized by the development of type 2 diabetes mellitus combined with symptoms of androgen (male trait hormone) overproduction, such as excessive facial and body hair. Achard syndrome most often occurs in postmenopausal women but can also occur in female adolescents and young women.
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What are the symptoms of Achard Syndrome?
Symptoms of Achard syndrome appear as the onset of type 2 diabetes, for which symptoms may include excessive thirst and appetite, weight loss, high glucose levels in urine, frequent urination, and symptoms of androgen overproduction, such as excess body hair (hirsutism), especially facial hair such as the development of a beard, receding hairline, deeper voice, clitoral enlargement, obesity, and infertility. Additional symptoms may include absent, infrequent, or very light menstruation, and acanthosis nigricans (darkening in skin folds). In female adolescents or young women, Achard may also be diagnosed as polycystic ovary syndrome (PCOS).
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What are the current treatments for Achard Syndrome?
Treatment for Achard syndrome includes diet therapy and/or insulin or other diabetes medications and oral contraceptives to control androgen overproduction in young women. Postmenopausal women with Achard syndrome are treated with hormone replacement therapy. Some individuals with Achard syndrome may be treated with anti-androgen therapy. Excess facial and body hair can be removed with cosmetic treatments, such as electrolysis or waxing.
Who are the top Achard Syndrome Local Doctors?
Elite
Highly rated in
13
conditions

Hôpital Bichat

Paris, FR 

Guillaume Jondeau is in Paris, France. Jondeau is rated as an Elite expert by MediFind in the treatment of Achard Syndrome. He is also highly rated in 13 other conditions, according to our data. His top areas of expertise are Marfan Syndrome, Achard Syndrome, Arachnodactyly, and Thoracic Aortic Aneurysm.

Distinguished
Highly rated in
28
conditions

Center For Medical Genetics

Antwerpen, VLG, BE 

Lut Van Laer is in Antwerpen, Belgium. Van Laer is rated as a Distinguished expert by MediFind in the treatment of Achard Syndrome. They are also highly rated in 28 other conditions, according to our data. Their top areas of expertise are Achard Syndrome, Arachnodactyly, Arterial Tortuosity Syndrome, and Marfan Syndrome.

 
 
 
 
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Distinguished
Highly rated in
12
conditions

University Of Cologne

Koeln, NW, DE 

Gerhard Sengle is in Koeln, Germany. Sengle is rated as a Distinguished expert by MediFind in the treatment of Achard Syndrome. He is also highly rated in 12 other conditions, according to our data. His top areas of expertise are Achard Syndrome, Weill-Marchesani Syndrome, GEMSS Syndrome, and Brachydactyly.

What are the latest Achard Syndrome Clinical Trials?
Effects of Modulation of the Dopaminergic System Using Methylphenidate on Memory and Executive Processes in Individuals With 22q11.2 Deletion Syndrome
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Pathogenetic Basis of Aortopathy and Aortic Valve Disease
What are the Latest Advances for Achard Syndrome?
Marfan syndrome and related disorders.
Severe neonatal Marfan syndrome with a novel mutation in the intron of the FBN1 gene: A case report.
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