Condition 101 About Acquired Methemoglobinemia

What is the definition of Acquired Methemoglobinemia?

Methemoglobinemia is a blood disorder in which the body cannot reuse hemoglobin because it is damaged. Hemoglobin is the oxygen-carrying molecule found in red blood cells. In some cases of methemoglobinemia, the hemoglobin is unable to carry enough oxygen to body tissues.

What are the causes for Acquired Methemoglobinemia?

Acquired methemoglobinemia results from exposure to certain drugs, chemicals, or foods.

The condition may also be passed down through families (inherited).

Blood

REFERENCES

Benz EJ, Ebert BL. Hemoglobin variants associated with hemolytic anemia, altered oxygen affinity, and methemoglobinemias. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 7th ed. Philadelphia, PA: Elsevier; 2018:chap 43.

Means RT. Approach to the anemias. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 149.

Vajpayee N, Graham SS, Bem S. Basic examination of blood and bone marrow. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 23rd ed. St Louis, MO: Elsevier; 2017:chap 30.

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Latest Advances On Acquired Methemoglobinemia

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Clinical Trials For Acquired Methemoglobinemia

Clinical Trial
  • Status: Recruiting
  • Phase: Phase 4
  • Intervention Type: Drug
  • Participants: 10
  • Start Date: July 6, 2018
Open Label Clinical Study to Evaluate the Safety and Efficacy of ProvayBlueTM (Methylene Blue) for the Treatment of Acquired Methemoglobinemia