MediFind
Condition

Actinic Keratosis

Condition 101

What is the definition of Actinic Keratosis?

Actinic keratosis is a small, rough, raised area on your skin. Often this area has been exposed to the sun over a long period of time.

Some actinic keratoses may develop into a type of skin cancer.

What are the alternative names for Actinic Keratosis?

Solar keratosis; Sun-induced skin changes - keratosis; Keratosis - actinic (solar); Skin lesion - actinic keratosis 

What are the causes for Actinic Keratosis?

Actinic keratosis is caused by exposure to sunlight.

You are more likely to develop it if you:

  • Have fair skin, blue or green eyes, or blond or red hair
  • Had a kidney or other organ transplant
  • Take medicines that suppress the immune system
  • Spend a lot of time each day in the sun (for example, if you work outdoors)
  • Had many severe sunburns early in life
  • Are older

What are the symptoms for Actinic Keratosis?

Actinic keratosis is usually found on the face, scalp, back of the hands, chest, or places that are often in the sun.

  • The skin changes begin as flat and scaly areas. They often have a white or yellow crusty scale on top.
  • The growths may be gray, pink, red, or the same color as your skin. Later they may become hard and wart-like or gritty and rough.
  • The affected areas may be easier to feel than see.

What are the current treatments for Actinic Keratosis?

Some actinic keratoses become squamous cell skin cancer. Have your provider look at all skin growths as soon as you find them. Your provider will tell you how to treat them.

Growths may be removed by:

  • Burning (electrical cautery)
  • Scraping away the lesion and using electricity to kill any remaining cells (called curettage and electrodesiccation)
  • Cutting the tumor out and using stitches to place the skin back together (called excision)
  • Freezing (cryotherapy, which freezes and kills the cells)

If you have many of these skin growths, your doctor may recommend:

  • A special light treatment called photodynamic therapy
  • Chemical peels
  • Skin creams, such as 5-fluorouracil (5-FU) and imiquimod

What is the outlook (prognosis) for Actinic Keratosis?

A small number of these skin growths turn into squamous cell carcinoma.

When should I contact a medical professional for Actinic Keratosis?

Call your provider if you see or feel a rough or scaly spot on your skin, or if you notice any other skin changes.

How do I prevent Actinic Keratosis?

The best way to lower your risk for actinic keratosis and skin cancer is to learn how to protect your skin from sun and ultraviolet (UV) light.

Things you can do to lower your exposure to sunlight include:

  • Wear clothing such as hats, long-sleeved shirts, long skirts, or pants.
  • Try to avoid being in the sun during midday, when ultraviolet light is most intense.
  • Use high-quality sunscreens, preferably with a sun protection factor (SPF) rating of at least 30. Pick a broad spectrum sunscreen that blocks both UVA and UVB light.
  • Apply sunscreen before going out into the sun, and reapply often -- at least every 2 hours while in the sun.
  • Use sunscreen year-round, including in the winter.
  • Avoid sun lamps, tanning beds, and tanning salons.

Other things to know about sun exposure:

  • Sun exposure is stronger in or near surfaces that reflect light, such as water, sand, concrete, and areas painted white.
  • Sunlight is more intense at the beginning of the summer.
  • Skin burns faster at higher altitudes.

REFERENCES

Habif TP. Premalignant and malignant nonmelanoma skin tumors. In: Habif TP, ed. Clinical Dermatology: A Color Guide to Diagnosis and Therapy. 6th ed. Philadelphia, PA: Elsevier; 2016:chap 21.

Soyer HP, Rigel DS, McMeniman E. Actinic keratosis, basal cell carcinoma, and squamous cell carcinoma. In: Bolognia JL, Schaffer JV, Cerroni L, eds. Dermatology. 4th ed. Philadelphia, PA: Elsevier; 2018:chap 108.

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Latest Research

Latest Advance
Study
  • Condition: Actinic Keratosis
  • Journal: Journal of drugs in dermatology : JDD
  • Treatment Used: Various
  • Number of Patients: 429
  • Published —
In this study, researchers sought to determine the best treatment for actinic keratosis in the real world.
Latest Advance
Study
  • Condition: Tumors of the Eyelid and Periorbital Region
  • Journal: Klinische Monatsblatter fur Augenheilkunde
  • Treatment Used: Surgery
  • Number of Patients: 349
  • Published —
This study analyzed the results of interdisciplinary treatment of periorbital and eyelid non-melanotic malignoma.
Latest Advance
Study
  • Condition: Actinic Keratosis in Patients with Xeroderma Pigmentosum in Africa
  • Journal: Photodiagnosis and photodynamic therapy
  • Treatment Used: Daylight photodynamic therapy
  • Number of Patients: 13
  • Published —
In this study, researchers evaluated the effects of using daylight photodynamic therapy for the treatment of actinic keratosis in patients with xeroderma pigmentosum in Africa.
Latest Advance
Study
  • Condition: Actinic keratosis
  • Journal: Journal of the European Academy of Dermatology and Venereology : JEADV
  • Treatment Used: Combination of therapies
  • Number of Patients: 0
  • Published —
The study researched the outcomes of combination therapies for patients with actinic keratosis.