Learn About Actinic Keratosis

What is the definition of Actinic Keratosis?

Actinic keratosis is a small, rough, raised area on your skin. Often this area has been exposed to the sun over a long period of time.

Some actinic keratoses may develop into a type of skin cancer.

What are the alternative names for Actinic Keratosis?

Solar keratosis; Sun-induced skin changes - keratosis; Keratosis - actinic (solar); Skin lesion - actinic keratosis

What are the causes of Actinic Keratosis?

Actinic keratosis is caused by exposure to sunlight.

You are more likely to develop it if you:

  • Have fair skin, blue or green eyes, or blond or red hair
  • Had a kidney or other organ transplant
  • Take medicines that suppress the immune system
  • Spend a lot of time each day in the sun (for example, if you work outdoors)
  • Had many severe sunburns early in life
  • Are older
What are the symptoms of Actinic Keratosis?

Actinic keratosis is usually found on the face, scalp, back of the hands, chest, or places that are often in the sun.

  • The skin changes begin as flat and scaly areas. They often have a white or yellow crusty scale on top.
  • The growths may be gray, pink, red, or the same color as your skin. Later, they may become hard and wart-like or gritty and rough.
  • The affected areas may be easier to feel than see.
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What are the current treatments for Actinic Keratosis?

Some actinic keratoses become squamous cell skin cancer. Have your provider look at all skin growths as soon as you find them. Your provider will tell you how to treat them.

Growths may be removed by:

  • Burning (electrical cautery)
  • Scraping away the lesion and using electricity to kill any remaining cells (called curettage and electrodesiccation)
  • Cutting the tumor out and using stitches to place the skin back together (called excision)
  • Freezing (cryotherapy, which freezes and kills the cells)

If you have many of these skin growths, your doctor may recommend:

  • A special light treatment called photodynamic therapy
  • Chemical peels
  • Skin creams, such as 5-fluorouracil (5-FU) and imiquimod
Who are the top Actinic Keratosis Local Doctors?

Sanford Medical Center

1301 W 18th St, 
Sioux Falls, SD 
 0.9 mi
Accepting New Patients

Renee Siegmann is a Dermatologist in Sioux Falls, South Dakota. Dr. Siegmann and is rated as a Distinguished provider by MediFind in the treatment of Actinic Keratosis. Her top areas of expertise are Bowen's Disease, Actinic Keratosis, Warts, and Seborrheic Keratosis. Dr. Siegmann is currently accepting new patients.

Sanford Medical Center

1305 W 18 St, 
Sioux Falls, SD 
 0.9 mi
Accepting New Patients

Jacob Kusmak is a Dermatologist in Sioux Falls, South Dakota. Dr. Kusmak and is rated as a Distinguished provider by MediFind in the treatment of Actinic Keratosis. His top areas of expertise are Melanoma, Familial Atypical Multiple Mole Melanoma Syndrome, Giant Congenital Melanocytic Nevus, and Giant Congenital Nevus. Dr. Kusmak is currently accepting new patients.

 
 
 
 
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Sanford Medical Center

1305 W 18 St, 
Sioux Falls, SD 
 0.9 mi
Accepting New Patients

Jocelyn Frohm is a Dermatologist in Sioux Falls, South Dakota. Dr. Frohm and is rated as a Distinguished provider by MediFind in the treatment of Actinic Keratosis. Her top areas of expertise are Bowen's Disease, Actinic Keratosis, Warts, and Seborrheic Keratosis. Dr. Frohm is currently accepting new patients.

What is the outlook (prognosis) for Actinic Keratosis?

A small number of these skin growths turn into squamous cell carcinoma.

When should I contact a medical professional for Actinic Keratosis?

Contact your provider if you see or feel a rough or scaly spot on your skin, or if you notice any other skin changes.

How do I prevent Actinic Keratosis?

The best way to lower your risk for actinic keratosis and skin cancer is to learn how to protect your skin from sun and ultraviolet (UV) light.

Things you can do to lower your exposure to sunlight include:

  • Wear clothing such as hats, long-sleeved shirts, long skirts, or pants.
  • Try to avoid being in the sun during midday, when ultraviolet light is most intense.
  • Use high-quality sunscreens, preferably with a sun protection factor (SPF) rating of at least 30. Pick a broad-spectrum sunscreen that blocks both UVA and UVB light.
  • Apply sunscreen before going out into the sun, and reapply often -- at least every 2 hours while in the sun.
  • Use sunscreen year-round, including in the winter.
  • Avoid sun lamps, tanning beds, and tanning salons.

Other things to know about sun exposure:

  • Sun exposure is stronger in or near surfaces that reflect light, such as water, sand, snow, concrete, and areas painted white.
  • Sunlight is more intense at the beginning of the summer.
  • Skin burns faster at higher altitudes.
What are the latest Actinic Keratosis Clinical Trials?
A Single Center, Observational Study to Evaluate the Effectiveness and Safety of Cryotherapy in Combination with 10% ALA Gel Red Light PDT in the Treatment of Actinic Keratosis on the Full Face.

Summary: 40 patients randomized 1:1 to receive cryotherapy followed by 10% ALA gel Red light PDT vs. to 10% ALA gel Red Light PDT followed by cryotherapy.

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Evaluation of the Clinical Utility of a New Diagnostic Support Tool, Based on Electrical Impedance Spectroscopy (NEVISENSE), for Keratinocyte Skin Cancer

Summary: This is a prospective study to assess efficacy of the Nevisense device in identifying keratinocyte skin cancer (KC) in patients suspected of having skin cancer based on the initial physician's assessment. All skin lesions with a suspicion of Basal cell carcinoma (BCC), Invasive Squamos cell Carcinoma (iSCC), Bowen's disease (BD) or actinic keratosis (AK) and destined for excision or biopsy for fur...

Who are the sources who wrote this article ?

Published Date: November 18, 2022
Published By: Elika Hoss, MD, Assistant Professor of Dermatology, Mayo Clinic, Scottsdale, AZ. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

American Academy of Dermatology Association website. Actinic keratosis: diagnosis and treatment. www.aad.org/public/diseases/skin-cancer/actinic-keratosis-treatment. Updated February 23, 2022. Accessed December 2, 2022.

Ball JW, Dains JE, Flynn JA, Solomon BS, Stewart RW. Skin, hair, and nails. In: Ball JW, Dains JE, Flynn JA, Solomon BS, Stewart RW, eds. Siedel's Guide to Physical Examination. 10th ed. St Louis, MO: Elsevier; 2023:chap 9.

Dinulos JGH. Premalignant and malignant nonmelanoma skin tumors. In: Dinulos JGH, ed. Habif's Clinical Dermatology. 7th ed. Philadelphia, PA: Elsevier; 2021:chap 21.

Gawkrodger DJ, Ardern-Jones MR. Pigmentation. In: Gawkrodger DJ, Ardern-Jones MR, eds. Dermatology: An Illustrated Colour Text. 7th ed. Philadelphia, PA: Elsevier; 2021:chap 42.

Soyer HP, Rigel DS, McMeniman E. Actinic keratosis, basal cell carcinoma, and squamous cell carcinoma. In: Bolognia JL, Schaffer JV, Cerroni L, eds. Dermatology. 4th ed. Philadelphia, PA: Elsevier; 2018:chap 108.