Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study is following up on previous studies that have demonstrated that geriatric subjects respond different to ultraviolet B (UVB) light than young subjects. The treatment of geriatric skin with dermal rejuvenation therapies (dermabrasion, fractionated laser resurfacing) restores the appropriate UVB response. Ongoing studies have tested the ability of fractionated laser resurfacing (FLR) to assess how long this wounding effect lasts-and have found that this appears to be a durable response which lasts for at least two years. The findings that FLR protects geriatric skin at two years is the impetus for this study. This study is an interventional study to assess if FLR treatment of one forearm of geriatric subjects with multiple actinic keratosis will result in the short-term removal of actinic keratosis, and the long-term decrease in levels of future actinic keratosis and other non-melanoma skin cancers in comparison to the untreated arm. Study length and visit: The first part of the study is completed in 1 day then there are follow up visits at 90 days and every 6 months for 5 years.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 60
Healthy Volunteers: f
View:

• Diagnosed with Actinic Keratosis within the past 6 months

• At least 60 years of age, or older

• Ability to comprehend procedures and risks versus benefits

• Able to provide Informed Consent

• Fair Skin (Fitzpatrick Type I or II)

• Possess both Right and Left Forearms

Locations
United States
Ohio
Dayton VA Medical Center
RECRUITING
Dayton
Contact Information
Primary
Manager, Clinical Research Operations
pturesearch@wrightstatephysicians.org
937-245-7500
Backup
Regulatory Specialist
pturesearch@wrightstatephysicians.org
937-245-7500
Time Frame
Start Date: 2018-01-10
Estimated Completion Date: 2028-12
Participants
Target number of participants: 72
Treatments
Experimental: Factionated Laser Resurfacing - Right Arm
Right forearm treatment of fractionated laser resurfacing.
Experimental: Factionated Laser Resurfacing - Left Arm
Left forearm treatment of fractionated laser resurfacing.
Related Therapeutic Areas
Sponsors
Leads: Wright State University

This content was sourced from clinicaltrials.gov