• Over 18yrs of age

• Willingness to participate in all required study activities and visits

• Willingness to sign the informed consent form

• Visible and palpable signs of diffuse actinic damage and actinic keratoses of mild to moderate severity located on the face

• Significant signs of photoaging, evaluated by investigator, that include any or all the following:

‣ Dyspigmentation

⁃ Solar lentigines

⁃ Telangiectasias

⁃ Diffuse erythema

⁃ Roughness and other textural changes

⁃ Fine lines

⁃ Wrinkles

⁃ Actinic bronzing