Multi-omics Characterization and Model Construction of Colchicine Anti-inflammatory Therapy Efficacy in Acute Coronary Syndromes Patients
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The aim of this prospective cohort study was to investigate the multi-omics characteristics of the efficacy of colchicine treatment in patients with ACS and to construct a model of efficacy. The main questions the study aims to answer are \- Specific mechanisms of colchicine therapy in patients with ACS; Mechanism-based modelling to identify the population that benefits from colchicine treatment.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• Between the ages of 18 and 80
• ACS (STEMI or NSTE-ACS)
• Patients to receive standardised drug therapy
• Able and willing to provide informed consent
Locations
Other Locations
China
Shanghai Tongji Hospital
RECRUITING
Shanghai
Contact Information
Primary
Xuebo Liu
lxb70@hotmail.com
13801926702
Time Frame
Start Date: 2025-07-01
Estimated Completion Date: 2027-07-01
Participants
Target number of participants: 380
Treatments
Experimental: Colchicine treatment group
Adding low-dose colchicine on the basis of standardized treatment
No_intervention: control group
Standardized treatment
Related Therapeutic Areas
Sponsors
Leads: Shanghai Tongji Hospital, Tongji University School of Medicine