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Comparison of a Contemporary Sirolimus-eluting Stent (ihtDEStiny®) With Another Everolimus-eluting Stent (Xience™), Both With Permanent Polymers, in Patients With Acute Coronary Syndrome and de Novo Coronary Artery Lesions (DestinACSion Study)

Status: Recruiting
Location: See all (13) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

To evaluate the efficacy of the two DES (Drug Eluting Stent) used in terms of device-related adverse events at 12 months after PCI (Percutaneous Coronary Intervention). To compare the clinical safety and efficacy by comparing net clinical events (defined as the combination of ischemic and hemorrhagic events) of the two DES used at 12 months after PCI.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

⁃ Patients who meet ALL inclusion criteria will be included:

• Patients aged ≥18 years, and

• Patients diagnosed with an acute coronary syndrome (ACS), either SCASEST (Acute Coronary Syndrome without Persistent ST-Segment Elevation) or IAMCEST (Acute Myocardial Infarction with Persistent ST-Segment Elevation), for which they will undergo PCI, and

• Patients with de novo lesions in vessels with a reference diameter of ≥2.25 mm and ≤4.5 mm in whom implantation of one or more DES is clinically indicated, and

• Patients who have been informed of the characteristics of the study and have provided written informed consent.

Locations
Other Locations
Spain
Hospital Universitario San Juan Alicante
RECRUITING
Alicante
Hospital Universitari Germans Trias I Pujol
RECRUITING
Badalona
Hospital Universitari Vall d'Hebron
RECRUITING
Barcelona
Hospital Universitario Virgen de La Arrixaca
RECRUITING
El Palmar
Hospital Universitario La Paz
RECRUITING
Fuencarral-el Pardo
Hospital Universitario Juan Ramón Jiménez
RECRUITING
Huelva
Hospital Universitario de Leon
RECRUITING
León
Hospital Universitari Arnau de Vilanova
RECRUITING
Lleida
Hospital Universitario Lucus Agustí
RECRUITING
Lugo
Hospital Regional Universitario de Málaga
RECRUITING
Málaga
Hospital Universitario de Canarias
RECRUITING
San Cristóbal De La Laguna
Hospital Clínico Universitario de Santiago
RECRUITING
Santiago De Compostela
Hospital Clínico Universitario Lozano Blesa
RECRUITING
Zaragoza
Contact Information
Primary
Armando Pérez de Prado, MD, PhD
admin@fundacionepic.org
0034987876135
Backup
FUNDACION EPIC
iepic@fundacionepic.org
0034987876135
Time Frame
Start Date: 2025-12-19
Estimated Completion Date: 2030-10-15
Participants
Target number of participants: 2100
Treatments
Other: Active Comparator: ihtDEStiny® DES
Other: Experimental: Xience™ DES
Sponsors
Leads: Fundación EPIC

This content was sourced from clinicaltrials.gov