Condition 101 About Acute Erythroid Leukemia

What is the definition of Acute Erythroid Leukemia?

Acute erythroid leukemia is a very rare subtype of acute myeloid leukemia. Leukemia is a progressive cancer in which the bone marrow and other blood-forming organs produce undeveloped or abnormal white blood cells (leukocytes) that suppress the development of normal blood cells. Acute erythroid leukemia has two subtypes: 1) erythroid leukemia (erythroid/myeloid) and 2) pure erythroid leukemia and is considered to have a poor prognosis.

What are the symptoms for Acute Erythroid Leukemia?

Symptoms of acute erythroid leukemia include weakness, paleness, fever, hemorrhage (bleeding), enlarged liver and spleen (hepatosplenomegaly), low blood clotting factor (thrombocytopenia), and anemia.

What are the current treatments for Acute Erythroid Leukemia?

Treatment for acute erythroid leukemia may include bone marrow transplantation with high-intensity chemotherapy or stem cell transplantation, which is currently considered to be the best available treatment. Some elderly patients may be treated with erythropoietin and granulocyte colony stimulating factor (GCSF). Patients with multidrug resistance may be treated with cyclosporin A and cyclosporin D analogue PSC 833 (valspodar), which may be combined with cytotoxic agent (drug that kills cells). The drug, sorafenib, has been reported to bring about a successful remission in a patient with acute erythroid leukemia.

Top Global Doctors For Acute Erythroid Leukemia

JS
Elite
Juerg Schwaller
Basel, BS, CH
FB
Elite
Frederik O. Bagger
Copenhagen, DK
TM
Elite
Thomas Mercher
Villejuif, FR
YD
Distinguished
Yaacov David-Ben
Guiyang, CN

Latest Advances On Acute Erythroid Leukemia

  • Condition: Erythroleukemia
  • Journal: Zhongguo shi yan xue ye xue za zhi
  • Treatment Used: Navitoclax Combined with Daunorubicin
  • Number of Patients: 0
  • Published —
The study researched the use of navitoclax combined with daunorubicin for treating erythroleukemia.