Learn About Acute Erythroid Leukemia

What is the definition of Acute Erythroid Leukemia?
Acute erythroid leukemia is a very rare subtype of acute myeloid leukemia. Leukemia is a progressive cancer in which the bone marrow and other blood-forming organs produce undeveloped or abnormal white blood cells (leukocytes) that suppress the development of normal blood cells. Acute erythroid leukemia has two subtypes: 1) erythroid leukemia (erythroid/myeloid) and 2) pure erythroid leukemia and is considered to have a poor prognosis.
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What are the symptoms of Acute Erythroid Leukemia?
Symptoms of acute erythroid leukemia include weakness, paleness, fever, hemorrhage (bleeding), enlarged liver and spleen (hepatosplenomegaly), low blood clotting factor (thrombocytopenia), and anemia.
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What are the current treatments for Acute Erythroid Leukemia?
Treatment for acute erythroid leukemia may include bone marrow transplantation with high-intensity chemotherapy or stem cell transplantation, which is currently considered to be the best available treatment. Some elderly patients may be treated with erythropoietin and granulocyte colony stimulating factor (GCSF). Patients with multidrug resistance may be treated with cyclosporin A and cyclosporin D analogue PSC 833 (valspodar), which may be combined with cytotoxic agent (drug that kills cells). The drug, sorafenib, has been reported to bring about a successful remission in a patient with acute erythroid leukemia.
Who are the top Acute Erythroid Leukemia Local Doctors?
TM
Thomas Mercher
Elite
Highly rated in
6
conditions

Gustave Roussy

Paris, FR 75013

Thomas Mercher is in Paris, France. Mercher is rated as an Elite expert by MediFind in the treatment of Acute Erythroid Leukemia. He is also highly rated in 6 other conditions, according to our data. His top areas of expertise are Acute Erythroid Leukemia, Acute Megakaryoblastic Leukemia, Leukemia, and Acute Myeloid Leukemia.

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JS
Juerg Schwaller
Elite
Highly rated in
8
conditions

University Of Basel

University Children's Hospital 
Basel, BS, CH 4031

Juerg Schwaller is in Basel, Switzerland. Schwaller is rated as an Elite expert by MediFind in the treatment of Acute Erythroid Leukemia. They are also highly rated in 8 other conditions, according to our data. Their top areas of expertise are Acute Erythroid Leukemia, Acute Myeloid Leukemia, Leukemia, and Acute Myeloblastic Leukemia without Maturation.

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AT
Alexandar S. Tzankov
Elite
Highly rated in
28
conditions

University Hospital Basel

Basel, BS, CH 4031

Alexandar Tzankov is in Basel, Switzerland. Tzankov is rated as an Elite expert by MediFind in the treatment of Acute Erythroid Leukemia. He is also highly rated in 28 other conditions, according to our data. His top areas of expertise are Acute Erythroid Leukemia, Diffuse Large B-Cell Lymphoma, B-Cell Lymphoma, and Non-Hodgkin Lymphoma.

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What are the latest Acute Erythroid Leukemia Clinical Trials?
CD34+ Stem Cell Selection for Patients Receiving a Matched or Partially Matched Family or Unrelated Adult Donor Allogeneic Stem Cell Transplantation for Non-Malignant Disease
Who is this study for: Adult patients that are younger than 40 years old that require an Allogeneic Stem Cell Transplant
Status: Active, not recruiting
Start Date: March 2013
Intervention Type: Biological
Phase: Phase 1/Phase 2
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Summary: This study's goal is to determine the frequency and severity of acute graft versus host disease, to evaluate incidence of primary and secondary graft rejection, to assess event free survival and overall survival, to determine the time to neutrophil and platelet engraftment, to determine the time to immune reconstitution (including normalization of T, B and natural killer (NK) cell repertoire and I...
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A Phase III Randomized, Double-Blind Study of Induction (Daunorubicin/Cytarabine) and Consolidation (High-Dose Cytarabine) Chemotherapy + Midostaurin (PKC412) (IND #101261) or Placebo in Newly Diagnosed Patients < 60 Years of Age With FLT3 Mutated Acute Myeloid Leukemia (AML)
Who is this study for: Adult patients with Acute Myeloid Leukemia
Status: Active, not recruiting
Start Date: April 2008
Intervention Type: Drug, Other
Study Drugs: Cytarabine, Intensol, Daunorubicin
Phase: Phase 3
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Summary: The purpose of this study is to compare the effects, good and/or bad, of a standard chemotherapy regimen for AML that includes the drugs daunorubicin and cytarabine combined with or without midostaurin (also known as PKC412), to find out which is better. This research is being done because it is unknown whether the addition of midostaurin to chemotherapy treatment is better than chemotherapy treat...
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What are the Latest Advances for Acute Erythroid Leukemia?
Quantifying RNA synthesis at rate-limiting steps of transcription using nascent RNA-sequencing data.
Journal: STAR protocols
Published: January 17, 2022
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Summary: Quantifying RNA synthesis at rate-limiting steps of transcription using nascent RNA-sequencing data.
Identification of Spiro-Fused Pyrrolo3,4-apyrrolizines and Tryptanthrines as Potential Antitumor Agents: Synthesis and In Vitro Evaluation.
Journal: International journal of molecular sciences
Published: November 13, 2021
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Summary: Identification of Spiro-Fused Pyrrolo3,4-apyrrolizines and Tryptanthrines as Potential Antitumor Agents: Synthesis and In Vitro Evaluation.
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Transcriptomic profile of human erythroleukemia cells in response to Sargassum fusiforme polysaccharide and its structure analysis.
Journal: Chinese journal of natural medicines
Published: October 24, 2021
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Summary: Transcriptomic profile of human erythroleukemia cells in response to Sargassum fusiforme polysaccharide and its structure analysis.
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