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Condition

Leukemia

Symptoms, Doctors, Treatments, Research & More

Condition 101

What is the definition of Leukemia?

Leukemia is a type of blood cancer that begins in the bone marrow. Bone marrow is the soft tissue in the center of the bones, where blood cells are produced.

The term leukemia means white blood. White blood cells (leukocytes) are used by the body to fight infections and other foreign substances. Leukocytes are made in the bone marrow.

Leukemia leads to an uncontrolled increase in the number of white blood cells.

The cancerous cells prevent healthy red cells, platelets, and mature white cells (leukocytes) from being made. Life-threatening symptoms can then develop as normal blood cells decline.

The cancer cells can spread to the bloodstream and lymph nodes. They can also travel to the brain and spinal cord (the central nervous system) and other parts of the body.

Leukemia can affect children and adults.

Leukemias are divided into two major types:

  • Acute (which progresses quickly)
  • Chronic (which progresses more slowly)

The main types of leukemia are:

  • Acute lymphocytic leukemia (ALL)
  • Acute myelogenous leukemia (AML)
  • Chronic lymphocytic leukemia (CLL)
  • Chronic myelogenous leukemia (CML)
Bone
Acute
Auer
Chronic
Chronic
Chronic
Chronic

REFERENCES

Appelbaum FR. Acute leukemias in adults. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 95.

Hunger SP, Teachey DT, Grupp S, Aplenc R. Childhood leukemia. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 93.

Latest Research

Latest Advance
Study
  • Condition: Adults with Philadelphia Chromosome (Ph)-Positive Acute Lymphoblastic Leukemia (ALL)
  • Journal: The New England journal of medicine
  • Treatment Used: Dasatinib-Blinatumomab
  • Number of Patients: 63
  • Published —
This study evaluated dasatanib-blinatumomab for adults with Philadelphia chromosome (Ph)-positive acute lymphoblastic leukemia (type of cancer of the blood and bone marrow affecting the white blood cells; ALL).
Latest Advance
Study
  • Condition: Elderly Patients with Acute Myeloid Leukemia (AML)
  • Journal: Zhongguo shi yan xue ye xue za zhi
  • Treatment Used: Low-Intensity Traditional Chemotherapy
  • Number of Patients: 67
  • Published —
This study investigated the effectiveness of low-intensity traditional chemotherapy for elderly patients with acute myeloid leukemia (cancer of the blood and bone marrow; AML).