Acute Hepatic Porphyria (AHP)
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Acute Hepatic Porphyria (AHP) Overview

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Learn About Acute Hepatic Porphyria (AHP)

What is the definition of Acute Hepatic Porphyria (AHP)?
Acute hepatic porphyria is a genetic metabolic disorder caused by a defect in the enzyme that assists heme synthesis, which results in the accumulation of porphyrins. Heme is involved in the production of hemoglobin, or the oxygen-carrying element in the blood, and porphyrins are molecules that help produce heme. There are several types of hepatic porphyria, including acute intermittent porphyria, variegate porphyria, aminolevulinic acid dehydratase deficiency porphyria, hereditary coproporphyria, and porphyria cutanea tarda.
What are the symptoms of Acute Hepatic Porphyria (AHP)?
Symptoms of acute hepatic porphyria may include severe abdominal, chest, arm, leg, and back pain; nausea; vomiting; constipation; rapid heartbeat; high blood pressure; muscle weakness; sensory loss; multiple nerve pain; blistering rashes; excessive hair loss; dark or reddish-brown urine; low blood sodium levels; seizures; and psychosis.
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What are the current treatments for Acute Hepatic Porphyria (AHP)?
Treatment for acute hepatic porphyria includes the administration of pain medication and intravenous hemin; carbohydrate loading; intravenous hypertonic saline; seizure control with benzodiazepine, gabapentin, Propofol, or magnesium; and liver transplantation.
Who are the top Acute Hepatic Porphyria (AHP) Local Doctors?
Elite in Acute Hepatic Porphyria (AHP)
Dr. Karl Anderson
Gastroenterology
Elite in Acute Hepatic Porphyria (AHP)
Dr. Karl Anderson
Gastroenterology

University Of Texas Medical Branch

301 University Blvd, 
Galveston, TX 
409-747-0890
Languages Spoken:
English
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Karl Anderson is a Gastroenterologist practicing medicine in Galveston, Texas. Dr. Anderson is rated as an Elite provider by MediFind in the treatment of Acute Hepatic Porphyria (AHP). He is also highly rated in 2 other conditions, according to our data. His clinical expertise encompasses Porphyria, Acute Hepatic Porphyria (AHP), Hepatitis C, and Hepatitis.

Elite in Acute Hepatic Porphyria (AHP)
Ulrich Stolzel
Elite in Acute Hepatic Porphyria (AHP)
Ulrich Stolzel
Chemnitz, SN, DE 

Ulrich Stolzel practices practicing medicine in Chemnitz, Germany. Mr. Stolzel is rated as an Elite expert by MediFind in the treatment of Acute Hepatic Porphyria (AHP). He is also highly rated in 7 other conditions, according to our data. His clinical expertise encompasses Acute Hepatic Porphyria (AHP), Porphyria, Acute Intermittent Porphyria, Hereditary Coproporphyria, and Liver Transplant.

 
 
 
 
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Elite in Acute Hepatic Porphyria (AHP)
Eliane Sardh
Elite in Acute Hepatic Porphyria (AHP)
Eliane Sardh

Karolinska Institutet

Stockholm, AB, SE 

Eliane Sardh practices practicing medicine in Stockholm, Sweden. Ms. Sardh is rated as an Elite expert by MediFind in the treatment of Acute Hepatic Porphyria (AHP). She is also highly rated in 5 other conditions, according to our data. Her clinical expertise encompasses Acute Intermittent Porphyria, Acute Hepatic Porphyria (AHP), Porphyria, and Variegate Porphyria.

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What are the latest Acute Hepatic Porphyria (AHP) Clinical Trials?
ELEVATE, a Global Observational Longitudinal Prospective Registry of Patients With Acute Hepatic Porphyria (AHP)
ELEVATE, a Global Observational Longitudinal Prospective Registry of Patients With Acute Hepatic Porphyria (AHP)
Enrollment Status: Recruiting
Publish Date: February 17, 2026

Summary: This global patient registry is being conducted to characterize the natural history and real-world clinical management of patients with AHP, and to further characterize the real-world safety and effectiveness of givosiran and other approved AHP therapies.

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