Latest Advances

  • Condition: Relapsed and Refractory Philadelphia Negative B Cell Acute Lymphoblastic Leukemia
  • Journal: Transplantation and cellular therapy
  • Treatment Used: Allogeneic Hematopoietic Cell Transplantation
  • Number of Patients: 108
  • Published —
The objective of this study was to determine post-hematopoietic stem cell transplantation (HCT) relapse-free survival (RFS) in adult patients with relapsed and refractory (r/r) Philadelphia-chromosome negative (Phneg) B cell acute lymphoblastic leukemia (B-ALL).
  • Condition: Cytomegalovirus Reactivation
  • Journal: Le infezioni in medicina
  • Treatment Used: Letermovir
  • Number of Patients: 133
  • Published —
This study evaluated the effectiveness and safety of letermovir (LTV) for cytomegalovirus (CMV) prophylaxis in allogeneic hematopoietic stem cell transplantation (HSCT) recipients.
  • Condition: B-Cell Acute Lymphoblastic Leukemia
  • Journal: JAMA
  • Treatment Used: Postreinduction Therapy Consolidation With Blinatumomab vs Chemotherapy
  • Number of Patients: 669
  • Published —
The aim of the study was to determine whether substituting blinatumomab for intensive chemotherapy in consolidation therapy would improve survival in children, adolescents, and young adults with high- and intermediate-risk first relapse of b-cell acute lymphoblastic leukemia.
  • Condition: Children With High-risk First-Relapse B-Cell Acute Lymphoblastic Leukemia
  • Journal: JAMA
  • Treatment Used: Blinatumomab versus Standard Intensive Multidrug Chemotherapy before Allogeneic Hematopoietic Stem Cell Transplant
  • Number of Patients: 108
  • Published —
The study researched the use of blinatumomab versus chemotherapy on event-free survival among children with high-risk first-relapse B-cell acute lymphoblastic leukemia.
  • Condition: B-cell Malignancies, Mantle cell lymphoma, and Multiple Myeloma
  • Journal: Frontiers in immunology
  • Treatment Used: CAR T-Cell Therapy
  • Number of Patients: 0
  • Published —
This article discusses the use of CAR T-cell therapy in the treatment of patients with B-cell malignancies, mantle cell lymphoma, and multiple myeloma.
  • Condition: Adolescent and Young Adult (AYA) Acute Lymphoblastic Leukemia (ALL)
  • Journal: Blood advances
  • Treatment Used: Modified BFM-90 Protocol
  • Number of Patients: 349
  • Published —
This study evaluated the outcomes and prognostic factors in the treatment of adolescent and young adult (AYA) patients with acute lymphoblastic leukemia (ALL) with a modified BFM-90 protocol.
  • Condition: Children with Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL)
  • Journal: Zhongguo shi yan xue ye xue za zhi
  • Treatment Used: Tyrosine Kinase Inhibitor (TKI) plus Chemotherapy and Allogeneic Hematopoietic Stem Cell Transplantation (allo-HSCT).
  • Number of Patients: 21
  • Published —
This study analyzed the outcomes of children with Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ALL) treated with tyrosine kinase inhibitor (TKI) plus chemotherapy and allogeneic hematopoietic stem cell transplantation (allo-HSCT).
  • Condition: Children with Acute Lymphoblastic Leukemia (ALL)
  • Journal: Blood
  • Treatment Used: Reduced-Intensity Therapy
  • Number of Patients: NULL
  • Published —
This study evaluated the effectiveness of reduced-intensity therapy for children with acute lymphoblastic leukemia (a type of blood cancer; ALL).
  • Condition: Children with Chronic Hepatitis B in Remission of Acute Lymphoblastic Leukemia
  • Journal: Georgian medical news
  • Treatment Used: Betargin
  • Number of Patients: 41
  • Published —
The purpose of the study is to assess the effectiveness of Betargin in complex management of patients with chronic hepatitis B in remission of acute lymphoblastic leukemia.
  • Condition: X-Linked Severe Combined Immunodeficiency Disease (SCID-X1)
  • Journal: Frontiers in immunology
  • Treatment Used: Gene Therapy
  • Number of Patients: 0
  • Published —
This review discusses gene therapy in the treatment of patients with X-linked severe immunodeficiency disease (SCID-X1).
  • Condition: Children with Acute Lymphocytic Leukemia (ALL)
  • Journal: Haematologica
  • Treatment Used: Pegylated E. Coli Asparaginase
  • Number of Patients: 889
  • Published —
This study evaluated the prevalence of antibodies against PEG among patients with acute lymphoblastic leukemia (ALL) prior to and/or immediately after their first dose of pegylated E.coli asparaginase (PEG-ASNase).
  • Condition: T-cell Lymphoblastic Lymphoma
  • Journal: Scientific reports
  • Treatment Used: Hematopoietic Stem Cell Transplantation
  • Number of Patients: 11
  • Published —
The study researched the safety and effectiveness of hematopoietic stem cell transplantation for treating T-cell lymphoblastic lymphoma.
Showing 1-12 of 308