Valacyclovir Monotherapy in Pain Management of Acute Apical Abscesses After Performing Emergency Chamber Opening; A Randomized Clinical Trial

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

This study is aimed to evaluate the efficacy of valacyclovir in reducing postoperative pain following emergency chamber opening for acute apical abscess . There will be 82 participants, (41 in each group) Group A will receive Valacyclovir Group B will receive standard treatment i.e. Naproxen Sodium. Pain level will be assessed by using Numeric rating scale for 6 days

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• Patient Age ≥18 years old

• Healthy patient American Society of Anesthesiologists (ASA) class l and ll.

• Patients having clinical evidence of pulp necrosis and acute apical abscess with radiographic signs of periapical disease.

• Main inclusion criteria is that patient should have moderate to severe pain, it can be calculated as:

• 1 to 3 as Mild pain. 4 to 6 as moderate pain. 7 to 10 as severe pain.

Locations
Other Locations
Pakistan
Dr. Yumna Shaheen Ali
RECRUITING
Karachi
Contact Information
Primary
Dr. Yumna Shaheen Ali
yumna.shaheen@duhs.edu.pk
03321349223
Backup
Dr. Fazal-ur-Rehman Qazi
qazi.rehman@duhs.edu.pk
02138771111
Time Frame
Start Date: 2024-03-27
Estimated Completion Date: 2024-05
Participants
Target number of participants: 82
Treatments
Experimental: Valacyclovir Group
participants will be given prescription of valacyclovir (2g immediate dose followed by 500mg 2 times daily for 3 days) along with the analgesic, Naproxen sodium, 550mg (SOS, if needed) Data will be recorded daily for 6 days
Active_comparator: Control Group
this is control group and is prescribed with analgesic, Naproxen sodium, 550mg (SOS, if needed) only
Related Therapeutic Areas
Sponsors
Leads: Dow University of Health Sciences

This content was sourced from clinicaltrials.gov