The Effect of Dexamethasone Administration Route on Pain and Inflammatory Response in PENG Block for Pediatric Hip Surgery

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

This study aims to assess the impact of the administration route of dexamethasone (intravenous vs. perineural) on postoperative pain, inflammatory response, and neuromonitoring parameters in pediatric patients undergoing hip surgery. The primary outcome is postoperative pain intensity measured using an age-appropriate pain scale at multiple time intervals. Secondary outcomes include inflammatory markers such as neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), opioid consumption, time to first rescue analgesia, and overall patient recovery. This randomized, double-blinded study seeks to improve pain management strategies and optimize anesthesia protocols in pediatric hip surgery.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 3 months
Maximum Age: 6
Healthy Volunteers: f
View:

• children scheduled for hip surgery

• body weight \> 5kg

Locations
Other Locations
Poland
Poznan University of Medical Sciences
RECRUITING
Poznan
Contact Information
Primary
Malgorztat Reysner, M.D. Ph.D.
mdomagalska@ump.edu.pl
+48 608762068
Time Frame
Start Date: 2025-02-01
Estimated Completion Date: 2026-03-31
Participants
Target number of participants: 60
Treatments
Active_comparator: perinerual dexamethasone
PENG block + perineural dexamethasone
Active_comparator: intravenous dexamethasone
PENG block + intravenous dexamethasone
Related Therapeutic Areas
Sponsors
Leads: Poznan University of Medical Sciences

This content was sourced from clinicaltrials.gov