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Transversus Abdominis Plane Block : A Comparative Study Between Bupivacaine vs Bupivacaine With Ketamine in Total Abdominal Hystrectomy

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 1/Phase 2
SUMMARY

The goal of this study is to know how effectively TAP block can reduce postoperative pain in total abdominal hystrectomy patients when given ketamine in addition to bupivacaine in TAP block and to compare it with the conventional TAP block with bupivacaine only. The main question it aims to answer is: Does intervention with ketamine in TAP block lowers the postoperative pain measured via visual analog scale and decreases the need for rescue analgesia? Patients will be assessed for pain in PACU( post anesthesia care unit), 6 hours, 12 hours and 24 hours postoperatively. Time of rescue analgesia will also be noted if given.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 25
Maximum Age: 65
Healthy Volunteers: f
View:

• Aged between 25 to 60 years.

• ASA grade I \& II.

• Undergoing total abdominal hysterectomy.

Locations
Other Locations
Pakistan
gynae operation theatre at Liaquat National Hospital
RECRUITING
Karachi
Time Frame
Start Date: 2025-11-01
Estimated Completion Date: 2026-04-01
Participants
Target number of participants: 30
Treatments
Active_comparator: TAP block with bupivacaine only
Experimental: TAP block with bupivacaine plus ketamine
Related Therapeutic Areas
Sponsors
Leads: Liaquat National Hospital & Medical College

This content was sourced from clinicaltrials.gov

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