Acute Respiratory Distress Syndrome (ARDS) Clinical Trials

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Ultra-protective Ventilation Monitored by Electrical Impedance Tomography in Patients With Severe Acute Respiratory Distress Syndrome on Veno-venous ECMO

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

For ECMO supported patients with severe ARDS (acute respiratory distress syndrome), usual care include use of ultraprotective mechanical ventilation with tidal volume and pressure reductions that might ultimately enhance lung protection of patients with ARDS. Although very low tidal might also cause pulmonary derecruitment. The aim of this study is to monitor effects of very low tidal volume on regression of overdistension and derecruitment using electrical impedance tomography. Secondary aim is to describe the evolution of the optimal PEEP (Positive End Expiratory Pressure) during the decrease of the tidal volume

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• aged ≥ 18 years

• patient with ARDS on venovenous (VV)-ECMO

• Written informed consent

• patient affiliated to a social security scheme

Locations
Other Locations
France
Service de médecine intensive - réanimation Hopital Pitié Salpêtrière
RECRUITING
Paris
Contact Information
Primary
Matthieu Pr SCHMIDT
matthieu.schmidt@aphp.fr
01 42 16 29 37
Time Frame
Start Date: 2023-03-11
Estimated Completion Date: 2027-05-11
Participants
Target number of participants: 50
Treatments
Experimental: Interventional
All patients included
Sponsors
Leads: Assistance Publique - Hôpitaux de Paris

This content was sourced from clinicaltrials.gov