AdenomyosisSymptoms, Doctors, Treatments, Advances & More
Learn About Adenomyosis
Adenomyosis is a thickening of the walls of the uterus. It occurs when endometrial tissue grows into the outer muscular walls of the uterus. Endometrial tissue forms the lining of the uterus.
Endometriosis interna; Adenomyoma; Pelvic pain - adenomyosis
The cause is not known. Sometimes, adenomyosis may cause the uterus to grow in size.
The condition most often occurs in women ages 35 to 50 who have had at least one pregnancy.
In many cases, there are no symptoms. When symptoms occur, they can include:
- Prolonged or heavy menstrual bleeding
- Painful menstrual periods, which gets worse
- Pelvic pain during intercourse
Most women have some adenomyosis as they get close to menopause. However, only a few will have symptoms. Most women do not need treatment.
Birth control pills and an IUD that has progesterone can help decrease heavy bleeding. Medicines such as ibuprofen or naproxen can also help manage pain.
Surgery to remove the uterus (hysterectomy) may be done in women with severe symptoms.
Jacques Donnez practices practicing medicine in Brussels, Belgium. Mr. Donnez is rated as an Elite expert by MediFind in the treatment of Adenomyosis. He is also highly rated in 9 other conditions, according to our data. His clinical expertise encompasses Uterine Fibroids, Menorrhagia, Infertility, Hysterectomy, and Hormone Replacement Therapy (HRT).
Shady Grove Fertility - Wesley Chapel
Anthony Imudia is a Reproductive Medicine provider practicing medicine in Wesley Chapel, Florida. Dr. Imudia is rated as a Distinguished provider by MediFind in the treatment of Adenomyosis. He is also highly rated in 3 other conditions, according to our data. His clinical expertise encompasses Infertility, Adenomyosis, Uterine Fibroids, Ectopic Pregnancy, and Endoscopy. Dr. Imudia is board certified in Obgyn and Rei.
Serdar Bulun is a Reproductive Medicine provider practicing medicine in Chicago, Illinois. Dr. Bulun is rated as a Distinguished provider by MediFind in the treatment of Adenomyosis. He is also highly rated in 6 other conditions, according to our data. His clinical expertise encompasses Uterine Fibroids, Endometriosis, Aromatase Deficiency, and Adenomyosis. Dr. Bulun is board certified in American Board Of Obstetrics And Gynecology - Obstetrics And Gynecology (Certified). Dr. Bulun is currently accepting new patients.
Symptoms most often go away after menopause. Surgery to remove the uterus often gets rid of symptoms completely.
Contact your provider if you develop symptoms of adenomyosis.
Background: Extracellular vesicles (EVs) are membrane-bound vesicles found in all biological fluids, containing various regulatory molecules, including microRNAs (miRNAs). It has been suggested that the EVs in human follicular fluid (the fluid surrounding the oocyte within the ovary) play a crucial role in oocyte development through these miRNAs. However, several methods exist for isolating these EVs from fol...
Summary: The uterus is a dynamic muscular organ that undergoes rhythmic, wave-like contractions known as endometrial peristalsis or endometrial waves. This muscular activity, which is an essential component of natural fertility, presents a nuanced and sometimes contradictory role in the context of assisted reproductive treatments. Endometrial peristalsis refers to the frequency, amplitude, and pattern of m...
Published Date: May 29, 2026
Published By: LaQuita Martinez, MD, Department of Obstetrics and Gynecology, Emory Johns Creek Hospital, Alpharetta, GA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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Dolan MS, Hill CC, Valea FA. Benign gynecologic lesions: vulva, vagina, cervix, uterus, oviduct, ovary, ultrasound imaging of pelvic structures. In: Gershenson DM, Lentz GM, Valea FA, Lobo RA, eds. Comprehensive Gynecology. 8th ed. Philadelphia, PA: Elsevier; 2022:chap 18.
Wei PK, Savicke AM, Levine D. The uterus. In: Rumack CM, Levine D, eds. Diagnostic Ultrasound. 6th ed. Philadelphia, PA: Elsevier; 2024:chap 28.