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Evaluation of the Efficacy and Tolerability of a Transcutaneous Electrical Nerve Stimulation (TENS) Device for the Management of Endometriosis-associated Pain

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

ELECTRE is a single-center, randomized, prospective, longitudinal, controlled, two-arm, single-blind study lasting 4 weeks (P1 investigation phase) after a 4-week run-in period. The study is followed by a 4-week extension phase (P2) in which all participants will be treated with active TENS. Randomization will be balanced according to a 1:1 ratio.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Healthy Volunteers: f
View:

• Women aged ≥ 18 years

• Endometriosis and/or adenomyosis diagnosed by imaging and/or histology

• Undergoing continuous, stable, and functional hormone treatment (with no menstruation) for at least 2 months

• No change in hormone treatment planned for the duration of the study

• Chronic pelvic pain for more than 6 months

• Pelvic pain at least equal to 2 out of 3 (on the intensity scale: 0 - None, 1 - Mild, 2 - Moderate, 3 - Severe)

• Agreeing to participate in the study

• Agrees to limit pain relief treatment during the study to level I painkillers paracetamol and Acupan® (nefopam), and the NSAID Antadys® (flurbiprofen)

• Has a computer, tablet, or cell phone with an internet connection

⁃ Is affiliated with a social security system or is a beneficiary of such a system

Locations
Other Locations
France
IFEM Endo, Clinique Tivoli-Ducos
RECRUITING
Bordeaux
Contact Information
Primary
Thomas LOBSTEIN
thomas.lobstein@monath-electronic.fr
+33-389497361
Time Frame
Start Date: 2026-03-15
Estimated Completion Date: 2027-12-31
Participants
Target number of participants: 92
Treatments
Experimental: Conventional TENS Group
Conventional TENS for 4 weeks
Active_comparator: Microstimulation TENS
Microstimulation TENS for 4 weeks
Related Therapeutic Areas
Sponsors
Leads: Monath Electronic

This content was sourced from clinicaltrials.gov