Learn About Adult Soft Tissue Sarcoma

What is the definition of Adult Soft Tissue Sarcoma?

Soft tissue sarcoma (STS) is cancer that forms in the soft tissue of the body. Soft tissue connects, supports, or surrounds other body parts. In adults, STS is rare.

There are many different types of soft tissue cancers. The type of sarcoma depends on the tissue it forms in:

  • Muscles
  • Tendons
  • Fat
  • Blood vessels
  • Lymph vessels
  • Nerves
  • Tissues in and around joints

The cancer can form almost anywhere, but is most common in the:

  • Head
  • Neck
  • Arms
  • Legs
  • Trunk
  • Abdomen
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What are the alternative names for Adult Soft Tissue Sarcoma?

STS; Leiomyosarcoma; Hemangiosarcoma; Kaposi's sarcoma; Lymphangiosarcoma; Synovial sarcoma; Neurofibrosarcoma; Liposarcoma; Fibrosarcoma; Malignant fibrous histiocytoma; Dermatofibrosarcoma; Angiosarcoma

What are the causes of Adult Soft Tissue Sarcoma?

It is not known what causes most sarcomas. But there are certain risk factors:

  • Some inherited diseases, such as Li-Fraumeni syndrome
  • Radiation therapy for other cancers
  • Exposure to certain chemicals, such as vinyl chloride or certain herbicides
  • Having swelling in the arms or legs for a long time (lymphedema)
What are the symptoms of Adult Soft Tissue Sarcoma?

In early stages, there are often no symptoms. As the cancer grows, it may cause a lump or swelling that keeps growing over time. Most lumps are NOT cancer.

Other symptoms include:

  • Pain, if it presses on a nerve, organ, blood vessel, or muscle
  • Blockage or bleeding in the stomach or intestines
  • Breathing problems
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What are the current treatments for Adult Soft Tissue Sarcoma?

Surgery is the most common treatment for STS.

  • In early stages, the tumor and some healthy tissue around it is removed.
  • Sometimes, just a small amount of tissue needs to be removed. Other times, a wider area of tissue must be removed.
  • With advanced cancers that form in an arm or leg, surgery may be followed by radiation or chemotherapy. Rarely, the limb may need to be amputated.

You also may have radiation or chemotherapy:

  • Used before surgery to help shrink the tumor to make it easier to remove the cancer
  • Used after surgery to kill any remaining cancer cells

Chemotherapy may be used to help kill cancer that has metastasized. This means it has spread to different areas of the body.

Who are the top Adult Soft Tissue Sarcoma Local Doctors?
Elite
Highly rated in
34
conditions
Hematology Oncology

Memorial Sloan Kettering Cancer Center

1275 York Ave 
New York, NY 10065

William Tap is a Hematologist Oncology doctor in New York, New York. Dr. Tap has been practicing medicine for over 22 years and is rated as an Elite doctor by MediFind in the treatment of Adult Soft Tissue Sarcoma. He is also highly rated in 34 other conditions, according to our data. His top areas of expertise are Adult Soft Tissue Sarcoma, Leiomyosarcoma, Gastrointestinal Stromal Tumor, and Epithelioid Sarcoma. He is board certified in Hematology/oncology and Internal Medicine and licensed to treat patients in California and New York. Dr. Tap is currently accepting new patients.

Elite
Highly rated in
35
conditions
Oncology

Memorial Sloan Kettering Cancer Center

1275 York Ave 
New York, NY 10065

Sandra Dangelo is an Oncologist in New York, New York. Dr. Dangelo has been practicing medicine for over 18 years and is rated as an Elite doctor by MediFind in the treatment of Adult Soft Tissue Sarcoma. She is also highly rated in 35 other conditions, according to our data. Her top areas of expertise are Adult Soft Tissue Sarcoma, Merkel Cell Carcinoma, Synovial Sarcoma, and Liposarcoma. She is board certified in Medical Oncology and licensed to treat patients in New York. Dr. Dangelo is currently accepting new patients.

 
 
 
 
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Elite
Highly rated in
31
conditions
Oncology

Memorial Sloan Kettering Cancer Center

1275 York Ave 
New York, NY 10065

Mrinal Gounder is an Oncologist in New York, New York. Dr. Gounder has been practicing medicine for over 18 years and is rated as an Elite doctor by MediFind in the treatment of Adult Soft Tissue Sarcoma. He is also highly rated in 31 other conditions, according to our data. His top areas of expertise are Adult Soft Tissue Sarcoma, Epithelioid Sarcoma, Desmoid Tumor, and Liposarcoma. He is board certified in Medical Oncology and licensed to treat patients in New York and Illinois. Dr. Gounder is currently accepting new patients.

What are the support groups for Adult Soft Tissue Sarcoma?

Cancer affects how you feel about yourself and your life. You can ease the stress of illness by joining a cancer support group. Sharing with others who have had the same experiences and problems can help you feel less alone.

Ask your provider to help you find a support group for people who have been diagnosed with STS.

What is the outlook (prognosis) for Adult Soft Tissue Sarcoma?

The outlook for people whose cancer is treated early is very good. Most people who survive 5 years can expect to be cancer-free at 10 years.

What are the possible complications of Adult Soft Tissue Sarcoma?

Complications include side effects from surgery, chemotherapy, or radiation.

When should I contact a medical professional for Adult Soft Tissue Sarcoma?

See your provider about any lump that grows in size or is painful.

How do I prevent Adult Soft Tissue Sarcoma?

The cause of most STSs isn't known and there is no way to prevent it. Knowing your risk factors and telling your provider when you first notice symptoms can increase your chance of surviving this type of cancer.

What are the latest Adult Soft Tissue Sarcoma Clinical Trials?
A Randomized Double-blind Phase II Study Evaluating the Role of Maintenance Therapy With Cabozantinib in High Grade Uterine Sarcoma (HGUtS) After Stabilization or Response to Doxorubicin +/- Ifosfamide Following Surgery or in Metastatic First Line Treatment
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A Phase I/II Open Label, Single Center, Study of the Combination of ALX148, Rituximab and Lenalidomide in Patients With Indolent and Aggressive B-Cell Non-Hodgkin Lymphoma
What are the Latest Advances for Adult Soft Tissue Sarcoma?
A long-term survivor of advanced retroperitoneal dedifferentiated liposarcoma: a successful multimodal approach with extended resection and chemotherapy.
Survival analysis of patients with recurrent or metastatic soft tissue sarcoma who were treated by cryoablation: A real-world retrospective study.
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Clinical observation of local intervention combined with camrelizumab and apatinib in the treatment of metastatic soft-tissue sarcoma.
Who are the sources who wrote this article ?

Published Date : July 28, 2020
Published By : Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. Editoria update 02/19/2021.

What are the references for this article ?

Contreras CM, Heslin MJ. Soft tissue sarcoma. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery. 20th ed. Philadelphia, PA: Elsevier; 2017:chap 31.

National Cancer Institute website. Adult soft tissue sarcoma treatment (PDQ) - health professional version. www.cancer.gov/types/soft-tissue-sarcoma/hp/adult-soft-tissue-treatment-pdq#section/all. Updated January 15, 2021. Accessed February19, 2021.

Van Tine BA. Sarcomas of soft tissue. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 90.