• Pathological and clinical diagnosis of advanced soft tissue sarcomas, pathological types include: fibrosarcoma, liposarcoma, undifferentiated pleomorphic sarcoma, epithelioid sarcoma, rhabdomyosarcoma, synovial sarcoma, alveolar soft-part sarcoma, leiomyosarcoma, clear cell sarcoma, malignant schwannoma, angiosarcoma.

• Consider immunotherapy or combined immunotherapy based on clinical judgement.

• Signed and dated informed consent form.

• Commitment to comply with research procedures and co-operation in the implementation of the full research process.

• Aged 6-80 years old.