Learn About ADULT Syndrome

What is the definition of ADULT Syndrome?
ADULT syndrome, also known as Acro-Dermato-Ungual-Lacrimal-Tooth syndrome, is a rare genetic autosomal dominant ectodermal dysplasia (abnormality of ectodermal tissues) caused by a TP63 mutation. In the human embryo, ectodermal tissues form many structures, including teeth, nails, hair, skin, fingers, and toes.
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What are the symptoms of ADULT Syndrome?
Symptoms of ADULT syndrome include abnormalities of ectodermal tissue, such as hypodontia (absence of one or more teeth); nail and lacrimal (tear) duct abnormalities; conjunctivitis; light sensitivity; hypoplastic breasts (insufficient mammary glandular tissue); hypotrichosis (little or no hair growth); blonde or light hair, eyelashes, and eyebrows; lack of axillary (underarm) hair; dry or thin skin; dermatitis or eczema; excessive freckling; as well as ectrodactyly (an abnormality of fingers or toes, such as split hand or foot, or a lack of fingers or toes), lack of fingerprints, and syndactyly (fused fingers or toes).
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What are the current treatments for ADULT Syndrome?
Treatment for ADULT syndrome requires a multidisciplinary team of specialists. Some deformities of the hands and feet may be treated with surgery, while dental treatment may include the use of dentures, dental implants, or bridges. Associated skin disorders, such as dry skin or eczema, may be treated with topical emollients. Abnormalities of the lacrimal (tear) ducts may require ophthalmological (eye) surgery.
Who are the top ADULT Syndrome Local Doctors?
Elite
Highly rated in
19
conditions

University Of Bologna

Bologna, IT 

Fabio Pizza is in Bologna, Italy. Pizza is rated as an Elite expert by MediFind in the treatment of ADULT Syndrome. He is also highly rated in 19 other conditions, according to our data. His top areas of expertise are Narcolepsy, Drowsiness, ADULT Syndrome, and Excessive Daytime Sleepiness.

Distinguished
Highly rated in
19
conditions

University Of Copenhagen

Institute Of Clinical Medicine 
Copenhagen, DK 

Poul Jennum is in Copenhagen, Denmark. Jennum is rated as a Distinguished expert by MediFind in the treatment of ADULT Syndrome. He is also highly rated in 19 other conditions, according to our data. His top areas of expertise are Drowsiness, Narcolepsy, ADULT Syndrome, and Excessive Daytime Sleepiness.

 
 
 
 
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Distinguished
Highly rated in
24
conditions

University Of Bologna

Metabolic And Neural Sciences 
Modena, IT 

Giuseppe Plazzi is in Modena, Italy. Plazzi is rated as a Distinguished expert by MediFind in the treatment of ADULT Syndrome. He is also highly rated in 24 other conditions, according to our data. His top areas of expertise are Narcolepsy, Drowsiness, Excessive Daytime Sleepiness, and Sleep Paralysis.

What are the latest ADULT Syndrome Clinical Trials?
MT2013-31: Allogeneic Hematopoietic Cell Transplantation for Inherited Metabolic Disorders and Severe Osteopetrosis Following Conditioning With Busulfan (Therapeutic Drug Monitoring), Fludarabine +/- ATG
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What are the Latest Advances for ADULT Syndrome?
Long-term effects of solriamfetol on quality of life and work productivity in participants with excessive daytime sleepiness associated with narcolepsy or obstructive sleep apnea.
Recognizing and Treating Excessive Daytime Sleepiness in Patients With Narcolepsy.
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Amifampridine to treat Lambert-Eaton myasthenic syndrome.