Alopecia Totalis

Condition 101

What is the definition of Alopecia Totalis?

Alopecia totalis (AT) is a condition characterized by the complete loss of hair on the scalp. It is an advanced form of alopecia areata a condition that causes round patches of hair loss. Although the exact cause of AT is unknown, it is thought to be an autoimmune condition in which the immune system mistakenly attacks the hair follicles. Roughly 20% of affected people have a family member with alopecia, suggesting that genetic factors may contribute to the development of AT. There is currently no cure for AT, but sometimes hair regrowth occurs on it's own, even after many years. in which the immune ...

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What are the alternative names for Alopecia Totalis?

  • Loss of all scalp hair

Latest Research

Latest Advance
  • Condition: Alopecia Totalis (AT)
  • Journal: Ugeskrift for laeger
  • Treatment Used: Tofacitinib
  • Number of Patients: 1
  • Published —
This study evaluated the treatment of tofacitinib in a patient with alopecia totalis (loss of all skull and facial hair; AT).
Latest Advance
  • Condition: Alopecia areata totalis
  • Journal: Dermatologic therapy
  • Treatment Used: Platelet rich plasma
  • Number of Patients: 10
  • Published —
The study researched the effect of platelet rich plasma on hair regrowth in patients with alopecia areata totalis.
Latest Advance
  • Condition: Refractory Alopecia Totalis
  • Journal: Acta dermato-venereologica
  • Treatment Used: Oral Tofacitinib
  • Number of Patients: 74
  • Published —
This study compared the clinical outcomes of the standard treatment for alopecia, oral tofacitinib, with other available medicines.
Latest Advance
  • Condition: Alopecia areata
  • Journal: The Australasian journal of dermatology
  • Treatment Used: Whole body treatments
  • Number of Patients: 768
  • Published —
The study researched the outcomes of whole body (systemic) treatments for patients with alopecia areata.

Clinical Trials

Clinical Trial
  • Status: Active, not recruiting
  • Study Type: Drug
  • Participants: 19
  • Start Date: January 12, 2019
Effectiveness and Safety of Tofacitinib in Patients With Extensive and Recalcitrant Alopecia Areata
Clinical Trial
  • Status: Active, not recruiting
  • Study Type: Behavioral
  • Participants: 15
  • Start Date: December 1, 2018
A Randomised Control Trial of Integrative Cognitive Behavioural Therapy for Alopecia: A Pilot Study