Condition 101 About Alopecia Totalis

What is the definition of Alopecia Totalis?

Alopecia totalis (AT) is a condition characterized by the complete loss of hair on the scalp. It is an advanced form of alopecia areata a condition that causes round patches of hair loss. Although the exact cause of AT is unknown, it is thought to be an autoimmune condition in which the immune system mistakenly attacks the hair follicles. Roughly 20% of affected people have a family member with alopecia, suggesting that genetic factors may contribute to the development of AT. There is currently no cure for AT, but sometimes hair regrowth occurs on it's own, even after many years.

What are the alternative names for Alopecia Totalis?

  • Loss of all scalp hair

Latest Advances On Alopecia Totalis

  • Condition: Alopecia Totalis (AT)
  • Journal: Ugeskrift for laeger
  • Treatment Used: Tofacitinib
  • Number of Patients: 1
  • Published —
This study evaluated the treatment of tofacitinib in a patient with alopecia totalis (loss of all skull and facial hair; AT).
  • Condition: Hereditary Vitamin D-Resistant Rickets
  • Journal: Journal of pediatric endocrinology & metabolism : JPEM
  • Treatment Used: Intermittent Intravenous Calcium
  • Number of Patients: 4
  • Published —
This case report describes 4 patients with hereditary vitamin D-resistant rickets that was treated using intermittent intravenous calcium.

Clinical Trials For Alopecia Totalis

Clinical Trial
  • Status: Recruiting
  • Phase: Phase 2
  • Intervention Type: Drug
  • Participants: 60
  • Start Date: September 15, 2020
A PHASE 2a, RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED STUDY INVESTIGATING THE SAFETY OF RITLECITINIB (PF-06651600) IN ADULT PARTICIPANTS WITH ALOPECIA AREATA
Clinical Trial
  • Status: Not yet recruiting
  • Phase: Phase 2
  • Intervention Type: Combination Product
  • Participants: 20
  • Start Date: February 5, 2020
Clinical Treatment of Alopecia Areata With Stem Cell Educator Therapy and Oral Minoxidil