Alpha-1 Antitrypsin Deficiency (AATD) Latest Advances

Find the Latest Research About Alpha-1 Antitrypsin Deficiency (AATD)

Last Updated: 06/30/2026

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Found 4037 publications

Undetected mutations across different serum alpha1 antitrypsin thresholds: An analysis of the avatar cohort.

Undetected mutations across different serum alpha1 antitrypsin thresholds: An analysis of the avatar cohort.

Journal: Pulmonology
Published: March 31, 2026

Adaptive Regulation of mTOR Activity by AMPK, Akt, and ATF6 Pathways in Pi*Z Alpha-1 Antitrypsin Deficient Hepatocytes.

Adaptive Regulation of mTOR Activity by AMPK, Akt, and ATF6 Pathways in Pi*Z Alpha-1 Antitrypsin Deficient Hepatocytes.

Journal: Biomolecules
Published: February 11, 2026

Alpha-1 Antitrypsin Deficiency-Associated Chronic Obstructive Pulmonary Disease.

Alpha-1 Antitrypsin Deficiency-Associated Chronic Obstructive Pulmonary Disease.

Journal: Medicina (Kaunas, Lithuania)
Published: February 09, 2026

Isolated GGT elevation in prolonged neonatal jaundice: detection of heterozygous alpha-1 antitrypsin deficiency.

Isolated GGT elevation in prolonged neonatal jaundice: detection of heterozygous alpha-1 antitrypsin deficiency.

Journal: BMJ case reports
Published: February 02, 2026

Liver Transplantation Reduces the Rate of Lung Function Decline in Severe Alpha-1-Antitrypsin Deficiency: A Case-Control Analysis.

Liver Transplantation Reduces the Rate of Lung Function Decline in Severe Alpha-1-Antitrypsin Deficiency: A Case-Control Analysis.

Journal: Chest
Published: January 08, 2026

Advances in orphan drug development for alpha-1 antitrypsin deficiency: a 2025 update from the FDA and EMA.

Advances in orphan drug development for alpha-1 antitrypsin deficiency: a 2025 update from the FDA and EMA.

Journal: Therapeutic advances in respiratory disease
Published: January 07, 2026

Alpha-1 Antitrypsin Deficiency Beyond COPD and Emphysema: A Narrative Review.

Alpha-1 Antitrypsin Deficiency Beyond COPD and Emphysema: A Narrative Review.

Journal: Medical sciences (Basel, Switzerland)
Published: December 29, 2025

Case Report: Pseudomonas liver abscess in a previously healthy child with homozygous pathogenic S allele variant of the SERPINA1 gene.

Case Report: Pseudomonas liver abscess in a previously healthy child with homozygous pathogenic S allele variant of the SERPINA1 gene.

Journal: Frontiers in immunology
Published: November 28, 2025

The mechanism of pathogenic α1-antitrypsin aggregation in the human liver.

The mechanism of pathogenic α1-antitrypsin aggregation in the human liver.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: November 13, 2025

Alpha-1 Antitrypsin Deficiency: Current Landscape of Detection, Management, and Treatment.

Alpha-1 Antitrypsin Deficiency: Current Landscape of Detection, Management, and Treatment.

Journal: Advances in therapy
Published: November 11, 2025

Prevalence of liver disease and liver transplantation in pediatric ZZ alpha-1 antitrypsin deficiency: A systematic review and meta-analysis.

Prevalence of liver disease and liver transplantation in pediatric ZZ alpha-1 antitrypsin deficiency: A systematic review and meta-analysis.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
Published: November 08, 2025

Pediatric Liver Diseases: Next-Generation Therapies.

Pediatric Liver Diseases: Next-Generation Therapies.

Journal: Clinics in liver disease
Published: October 18, 2025
Showing 1-12 of 4,037

Last Updated: 06/30/2026