Alpha-1 Antitrypsin Deficiency (AATD) Latest Advances

Undetected mutations across different serum alpha1 antitrypsin thresholds: An analysis of the avatar cohort.

Journal: Pulmonology

Published: March 31, 2026

Isolated GGT elevation in prolonged neonatal jaundice: detection of heterozygous alpha-1 antitrypsin deficiency.

Journal: BMJ case reports

Published: February 02, 2026

Liver transplantation reduces the rate of lung function decline in severe Alpha-1-antitrypsin deficiency: A case-control analysis.

Journal: Chest

Published: January 08, 2026

Advances in orphan drug development for alpha-1 antitrypsin deficiency: a 2025 update from the FDA and EMA.

Journal: Therapeutic advances in respiratory disease

Published: January 07, 2026

Alpha-1 Antitrypsin Deficiency Beyond COPD and Emphysema: A Narrative Review.

Journal: Medical sciences (Basel, Switzerland)

Published: December 29, 2025

The mechanism of pathogenic α1-antitrypsin aggregation in the human liver.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: November 13, 2025

Alpha-1 Antitrypsin Deficiency: Current Landscape of Detection, Management, and Treatment.

Journal: Advances in therapy

Published: November 11, 2025

Pediatric Liver Diseases: Next-Generation Therapies.

Journal: Clinics in liver disease

Published: October 18, 2025

Lung transplantation for chronic obstructive pulmonary disease patients: an overview.

Journal: Current opinion in pulmonary medicine

Published: October 09, 2025

Multi-Society Expert Panel Consensus Guidance Regarding Clinical Assessment and Clinical Trial Endpoints in Adults With Alpha-1 Antitrypsin Deficiency-Associated Liver Disease.

Journal: Gastroenterology

Published: October 08, 2025

Rapid design and production of Alpha-1 antitrypsin fusion proteins in a plant-based cell-free expression system.

Journal: Free radical biology & medicine

Published: September 29, 2025

Pioglitazone reduces hepatic α-1 antitrypsin accumulation through autophagy and AMPK activation in α-1 antitrypsin-deficient mice.

Journal: American journal of physiology. Gastrointestinal and liver physiology

Published: September 29, 2025

Alpha-1 Antitrypsin Deficiency (AATD) Latest Advances

Find the Latest Research About Alpha-1 Antitrypsin Deficiency (AATD)

Undetected mutations across different serum alpha1 antitrypsin thresholds: An analysis of the avatar cohort.

Undetected mutations across different serum alpha1 antitrypsin thresholds: An analysis of the avatar cohort.

Isolated GGT elevation in prolonged neonatal jaundice: detection of heterozygous alpha-1 antitrypsin deficiency.

Isolated GGT elevation in prolonged neonatal jaundice: detection of heterozygous alpha-1 antitrypsin deficiency.

Liver transplantation reduces the rate of lung function decline in severe Alpha-1-antitrypsin deficiency: A case-control analysis.

Liver transplantation reduces the rate of lung function decline in severe Alpha-1-antitrypsin deficiency: A case-control analysis.

Advances in orphan drug development for alpha-1 antitrypsin deficiency: a 2025 update from the FDA and EMA.

Advances in orphan drug development for alpha-1 antitrypsin deficiency: a 2025 update from the FDA and EMA.

Alpha-1 Antitrypsin Deficiency Beyond COPD and Emphysema: A Narrative Review.

Alpha-1 Antitrypsin Deficiency Beyond COPD and Emphysema: A Narrative Review.

The mechanism of pathogenic α1-antitrypsin aggregation in the human liver.

The mechanism of pathogenic α1-antitrypsin aggregation in the human liver.

Alpha-1 Antitrypsin Deficiency: Current Landscape of Detection, Management, and Treatment.

Alpha-1 Antitrypsin Deficiency: Current Landscape of Detection, Management, and Treatment.

Pediatric Liver Diseases: Next-Generation Therapies.

Pediatric Liver Diseases: Next-Generation Therapies.

Lung transplantation for chronic obstructive pulmonary disease patients: an overview.

Lung transplantation for chronic obstructive pulmonary disease patients: an overview.

Multi-Society Expert Panel Consensus Guidance Regarding Clinical Assessment and Clinical Trial Endpoints in Adults With Alpha-1 Antitrypsin Deficiency-Associated Liver Disease.

Multi-Society Expert Panel Consensus Guidance Regarding Clinical Assessment and Clinical Trial Endpoints in Adults With Alpha-1 Antitrypsin Deficiency-Associated Liver Disease.

Rapid design and production of Alpha-1 antitrypsin fusion proteins in a plant-based cell-free expression system.

Rapid design and production of Alpha-1 antitrypsin fusion proteins in a plant-based cell-free expression system.

Pioglitazone reduces hepatic α-1 antitrypsin accumulation through autophagy and AMPK activation in α-1 antitrypsin-deficient mice.

Pioglitazone reduces hepatic α-1 antitrypsin accumulation through autophagy and AMPK activation in α-1 antitrypsin-deficient mice.