Learn About Alpha Thalassemia

What is the definition of Alpha Thalassemia?

Alpha thalassemia is a blood disorder that reduces the production of hemoglobin. Hemoglobin is the protein in red blood cells that carries oxygen to cells throughout the body.

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What are the causes of Alpha Thalassemia?

Alpha thalassemia typically results from deletions involving the HBA1 and HBA2 genes. Both of these genes provide instructions for making a protein called alpha-globin, which is a component (subunit) of hemoglobin.

How prevalent is Alpha Thalassemia?

Alpha thalassemia is a fairly common blood disorder worldwide. Thousands of infants with Hb Bart syndrome and HbH disease are born each year, particularly in Southeast Asia. Alpha thalassemia also occurs frequently in people from Mediterranean countries, Africa, the Middle East, India, and Central Asia.

Is Alpha Thalassemia an inherited disorder?

The inheritance of alpha thalassemia is complex. Each person inherits two alpha-globin alleles from each parent. If both parents are missing at least one alpha-globin allele, their children are at risk of having Hb Bart syndrome, HbH disease, or alpha thalassemia trait. The precise risk depends on how many alleles are missing and which combination of the HBA1 and HBA2 genes is affected.

Who are the top Alpha Thalassemia Local Doctors?
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Mahidol University

Department Of Pediatrics, Faculty Of Medicine Siriraj Hospital, Mahidol University 
Bangkok, TH 

Vip Viprakasit is in Bangkok, Thailand. Viprakasit is rated as an Elite expert by MediFind in the treatment of Alpha Thalassemia. They are also highly rated in 15 other conditions, according to our data. Their top areas of expertise are Alpha Thalassemia, Thalassemia, Anemia, and Beta Thalassemia.

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Highly rated in
16
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Division Of Hematology And Oncology

Department Of Pediatrics, Faculty Of Medicine, Chiang Mai University 
Chiang Mai, TH 50200

Pimlak Charoenkwan is in Chiang Mai, Thailand. Charoenkwan is rated as an Elite expert by MediFind in the treatment of Alpha Thalassemia. They are also highly rated in 16 other conditions, according to our data. Their top areas of expertise are Thalassemia, Alpha Thalassemia, Congenital Hemolytic Anemia, and Hemoglobinopathy.

 
 
 
 
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41
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Zhujiang New Town

Prenatal Diagnostic Center, Guangzhou Women And Children Medical Center, Jinsui Road 9 
Guangzhou, CN 51062

Dong-zhi Li is in Guangzhou, China. Li is rated as an Elite expert by MediFind in the treatment of Alpha Thalassemia. They are also highly rated in 41 other conditions, according to our data. Their top areas of expertise are Alpha Thalassemia, Thalassemia, Fetal Edema, and Hydrops Fetalis.

What are the latest Alpha Thalassemia Clinical Trials?
FAST Trial Registry: Prospective Observational Cohort Study of Fetal Atrial Flutter & Supraventricular Tachycardia
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Fetal Electrophysiologic Abnormalities in High-risk Pregnancies Associated With Fetal Demise
Who are the sources who wrote this article ?

Published Date:updated Last, June

Published By: National Institutes of Health

What are the Latest Advances for Alpha Thalassemia?
Extremely Rare Case of Fetal Anemia Due to Mitochondrial Disease Managed with Intrauterine Transfusion.
Síndrome en espejo con miocardiopatía no compactada en la madre y el feto. Reporte de caso.
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Fracture prevalence in thalassemia: a systematic review and meta-analysis.