Shrimp Sensitization and Allergy Among Patients With Edible Insect Allergy
This study aims to determine the prevalence of shrimp sensitization and clinical shrimp allergy among patients aged ≥7 years with confirmed allergy to edible insects, including silkworm, bamboo worm, and palm weevil. Participants undergo skin prick testing, specific IgE testing, ALEX2, immunoblot analysis, and risk-based oral food challenges to assess clinical cross-reactivity between edible insects and white shrimp and to help avoid unnecessary shrimp restriction.
• Patients aged 7 years or older with a history of allergy to one or more of the following edible insects: silkworm, bamboo worm, or palm weevil.
• Patients with a history of an acute allergic reaction to silkworm, bamboo worm, or sago palm weevil who meet at least one of the following criteria:
‣ Development of clinical symptoms consistent with an acute allergic reaction within 2 hours after ingestion of the implicated edible insect, with evidence of sensitization confirmed by a positive skin prick test (SPT) to that edible insect; or
⁃ A positive oral food challenge (OFC) to the edible insect previously associated with allergic symptoms (silkworm, bamboo worm, or sago palm weevil).